Krings Audrey, Geurten Marie, Lazari Ecaterina, Blairy Sylvie
Psychology and Neuroscience of Cognition Research Unit (PsyNCog), Université de Liège, Liège, Belgium.
National Fund for Scientific Research (FRS-FNRS), Psychology of Liège, Liège, Belgium.
Front Psychol. 2022 Jul 20;13:914094. doi: 10.3389/fpsyg.2022.914094. eCollection 2022.
This study tested whether the combination of BATD and Attention Training Technique (ATT) is effective to reduce depressive symptomatology and investigate the mechanisms of action underlying the effectiveness of treatment with a multiple N-of-1 trials.
Nine adults with depressive symptoms were randomly included in three different combinations of BATD and ATT, concurrent in Condition 1 and sequential in Conditions 2 and 3 (ATT followed by BATD and BATD followed by ATT, respectively). The sequential components allow investigating the specific changes that occur during the two distinct treatment phases. Multiple self-report and pre-post-assessments were conducted on generic mental health measures (depressive symptoms, life functioning, mood, and well-being) and intervention-specific measures (behavioral activation, behavioral avoidance, self-focused attention, cognitive control and rumination), with two-week and three-month follow-up assessments. We also measured treatment adherence with treatment attendance, homework compliance and a clinical interview.
Participants' attendance, homework compliance and satisfaction were acceptable in the three conditions, with higher adherence in Condition 1 and Condition 3. Eight participants out of nine reported a reduction in depressive symptomatology and five an improvement in well-being. Most of their progress was maintained 2 weeks after the intervention but not 3 months later. Conditions 1 and 2 seemed to be associated with a higher response to generic mental health measures in comparison with Condition 3. The three conditions were not associated with consistent changes in intervention-specific measures, except for rumination with five participants out of nine reporting an improvement in rumination immediately after the intervention and eight participants 2 weeks after the intervention. The concurrent format was associated with a better improvement in rumination immediately after the intervention. No specific changes of self-focused attention and rumination characterized ATT, and no specific changes of behavioral activation, behavioral avoidance and rumination characterized BATD.
Our three interventions were judged acceptable and showed positive short-term benefit for generic mental health measures and rumination maintained 2 weeks later, but not 3 months later. Results suggest that five sessions of concurrent treatment could be a better option than sequential formats. However, our data did not support the specificity of ATT and BATD treatments.
本研究测试了行为激活训练与注意训练技术(ATT)的联合使用是否能有效减轻抑郁症状,并通过多个单病例试验研究该治疗有效性背后的作用机制。
九名有抑郁症状的成年人被随机纳入行为激活训练与注意训练技术的三种不同组合中,在第1组中同时进行,在第2组和第3组中依次进行(分别是注意训练技术后接行为激活训练和行为激活训练后接注意训练技术)。依次进行的部分能够探究在两个不同治疗阶段发生的具体变化。针对一般心理健康指标(抑郁症状、生活功能、情绪和幸福感)以及特定干预指标(行为激活、行为回避、自我关注、认知控制和反刍思维)进行了多次自我报告和前后评估,并进行了为期两周和三个月的随访评估。我们还通过治疗出勤情况、家庭作业完成情况和临床访谈来衡量治疗依从性。
在三种情况下,参与者的出勤情况、家庭作业完成情况和满意度都可以接受,第1组和第3组的依从性更高。九名参与者中有八名报告抑郁症状有所减轻,五名报告幸福感有所改善。他们的大部分进展在干预后两周得以维持,但三个月后未维持。与第3组相比,第1组和第2组似乎与对一般心理健康指标的更高反应相关。除了反刍思维外,三种情况与特定干预指标的持续变化无关,九名参与者中有五名报告干预后立即反刍思维有所改善,八名参与者在干预后两周反刍思维有所改善。同时进行的形式与干预后立即反刍思维的更好改善相关。注意训练技术没有自我关注和反刍思维的特定变化特征,行为激活训练也没有行为激活、行为回避和反刍思维的特定变化特征。
我们的三种干预措施被认为是可接受的,并且对一般心理健康指标和两周后维持的反刍思维显示出短期积极益处,但三个月后未显示出该益处。结果表明,五节同时进行的治疗可能比依次进行的形式是更好选择。然而,我们的数据并不支持注意训练技术和行为激活训练治疗的特异性。