Fu Shi-Jia, Xu Jing-Bo, Liu Xin, Cao Yi-Min, Yi Ze-Xi, Zhou Li-Xia
Department of Medical Imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Front Neurol. 2022 Jul 22;13:875402. doi: 10.3389/fneur.2022.875402. eCollection 2022.
The intracranial venous system plays an important role in ensuring blood circulation and a stable blood supply to the fetal brain. In the present study, a cross-sectional area of the fetal straight sinus was quantitatively evaluated by fetal magnetic resonance imaging (MRI) to explore the method's clinical value.
The clinical and MRI data of 126 normal fetuses in mid-to-late stage pregnancies were retrospectively analyzed. The "dominant" sequence of the fetal straight sinus was selected, and the cross-sectional area of the lumen was measured at each gestational age to obtain the normal range at different ages and to analyze the developmental pattern and characteristics of the fetal straight sinus.
There were statistically significant differences in the cross-sectional area of the fetal straight sinus among different gestational ages ( < 0.05). The cross-sectional area of the fetal straight sinus was positively correlated with gestational age (coefficient of determination = 0.6892, < 0.05). That is, the cross-sectional area of the fetal straight sinus grew with increasing gestational age, and the regression equation was = 0.27 - 2.14 ( < 0.05). Additionally, there were five fetuses with cerebral venous abnormalities, including four with heart failure and one with venous sinus thrombosis.
Quantitative measurement of a cross-sectional area of the fetal straight sinus by MRI enhanced understanding of the anatomical features and developmental pattern of fetal cerebral veins and provided a reference for the clinical diagnosis of related diseases and investigation concerning pathogenesis.
颅内静脉系统在确保胎儿脑部血液循环和稳定血液供应方面发挥着重要作用。在本研究中，通过胎儿磁共振成像（MRI）对胎儿直窦的横截面积进行定量评估，以探讨该方法的临床价值。
回顾性分析126例中晚期妊娠正常胎儿的临床及MRI资料。选取胎儿直窦的“优势”序列，测量各孕周时管腔的横截面积，以获得不同孕周的正常范围，并分析胎儿直窦的发育模式和特征。
不同孕周胎儿直窦的横截面积差异有统计学意义（<0.05）。胎儿直窦的横截面积与孕周呈正相关（决定系数=0.6892，<0.05）。即胎儿直窦的横截面积随孕周增加而增大，回归方程为=0.27 - 2.14（<0.05）。此外，有5例胎儿存在脑静脉异常，其中4例伴有心力衰竭，1例伴有静脉窦血栓形成。
通过MRI对胎儿直窦横截面积进行定量测量，增强了对胎儿脑静脉解剖特征和发育模式的理解，并为相关疾病的临床诊断及发病机制研究提供了参考。
