Dunlop Boadie W, Rakofsky Jeffrey J, Mischoulon David, Mayberg Helen S, Kinkead Becky, Nierenberg Andrew A, Ziegler Thomas R, Fava Maurizio, Rapaport Mark H
Department of Psychiatry and Behavioral Sciences, Emory University, 12 Executive Park Drive NE, 3rd Floor Atlanta, GA 30329, USA.
Department of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA.
Pers Med Psychiatry. 2022 Mar-Apr;31-32. doi: 10.1016/j.pmip.2022.100091. Epub 2022 Jan 12.
Individuals experiencing socioeconomic deprivation consistently demonstrate poorer physical and mental health. Income alone is inadequate as a measure of socioeconomic status (SES); a better measure for assessing the deprivation status of individuals is needed.
The New Zealand Index of Socioeconomic Deprivation for Individuals, a validated, eight-item measure of deprivation, was modified to create the United States Index of Socioeconomic Deprivation for Individuals (USiDep). The questionnaire was administered to patients with major depressive disorder participating in two clinical trials. Spearman's correlation coefficients evaluated associations between USiDep scores with income and other measures associated with deprivation.
The USiDep was completed by 118 participants, demonstrating adequate internal consistency (Crohnbach's alpha = 0.766) and strong item-total correlations. USiDep scores were moderately correlated with past-year personal income (Spearman's rho = -0.362, p < .001) and several other measures related to deprivation, including body mass index, level of education, quality of life, severity of childhood traumatic events, self-reported physical health, and negative life events. Patients scoring 5 on the USiDep (the highest possible score, indicating greater deprivation) had significantly lower rates of remission after 12 weeks of treatment than those scoring ≤ 4 (1/12, 8.3% vs 40/98, 40.8%, respectively, p = .03), whereas the lowest income group showed no significant associations with outcomes.
The USiDep is a valid, brief questionnaire for assessing SES that has utility for clinical research and may serve as a predictor of treatment outcomes in clinical trials. Validation of the USiDep in healthy controls and other medically and psychiatrically ill populations is warranted.
经历社会经济剥夺的个体一直表现出较差的身心健康状况。仅收入不足以作为社会经济地位（SES）的衡量标准；需要一种更好的方法来评估个体的剥夺状况。
对经过验证的、包含八个项目的个体社会经济剥夺新西兰指数进行修改，以创建个体社会经济剥夺美国指数（USiDep）。该问卷被施用于参与两项临床试验的重度抑郁症患者。斯皮尔曼相关系数评估了USiDep分数与收入以及其他与剥夺相关的指标之间的关联。
118名参与者完成了USiDep问卷，显示出足够的内部一致性（克朗巴赫α系数 = 0.766）和较强的项目与总分相关性。USiDep分数与过去一年的个人收入（斯皮尔曼相关系数ρ = -0.362，p <.001）以及其他一些与剥夺相关的指标存在中度相关性，这些指标包括体重指数、教育水平、生活质量、童年创伤事件的严重程度、自我报告的身体健康状况以及负面生活事件。在USiDep上得分为5分（可能的最高分，表明剥夺程度更高）的患者在治疗12周后的缓解率显著低于得分≤4分的患者（分别为1/12，8.3% 对40/98，40.8%，p =.03），而收入最低的组与治疗结果无显著关联。
USiDep是一种有效的简短问卷，用于评估SES，对临床研究有用，并且可能作为临床试验中治疗结果的预测指标。有必要在健康对照以及其他患有医学和精神疾病的人群中对USiDep进行验证。
