Shader Maureen J, Luke Robert, McKay Colette M
Purdue University, Department of Speech, Language, and Hearing Sciences, 715 Clinic Drive, West Lafayette, IN 47907, USA.
The University of Melbourne, Department of Medical Bionics, Parkville, VIC 3010, Australia.
iScience. 2022 Jul 9;25(8):104737. doi: 10.1016/j.isci.2022.104737. eCollection 2022 Aug 19.
Sensory deprivation causes structural and functional changes in the human brain. Cochlear implantation delivers immediate reintroduction of auditory sensory information. Previous reports have indicated that over a year is required for the brain to reestablish canonical cortical processing patterns after the reintroduction of auditory stimulation. We utilized functional near-infrared spectroscopy (fNIRS) to investigate brain activity to natural speech stimuli directly after cochlear implantation. We presented 12 cochlear implant recipients, who each had a minimum of 12 months of auditory deprivation, with unilateral auditory- and visual-speech stimuli. Regardless of the side of implantation, canonical responses were elicited primarily on the contralateral side of stimulation as early as 1 h after device activation. These data indicate that auditory pathway connections are sustained during periods of sensory deprivation in adults, and that typical cortical lateralization is observed immediately following the reintroduction of auditory sensory input.
感觉剥夺会导致人类大脑的结构和功能发生变化。人工耳蜗植入可立即重新引入听觉感觉信息。先前的报告表明，在重新引入听觉刺激后，大脑需要一年以上的时间才能重新建立典型的皮质处理模式。我们利用功能近红外光谱技术（fNIRS）在人工耳蜗植入后直接研究大脑对自然语音刺激的活动。我们向12名人工耳蜗植入受者（每人至少有12个月的听觉剥夺）呈现单侧听觉和视觉语音刺激。无论植入侧如何，早在设备激活后1小时，典型反应主要在刺激的对侧诱发。这些数据表明，在成年人感觉剥夺期间，听觉通路连接得以维持，并且在重新引入听觉感觉输入后立即观察到典型的皮质侧化。
