Department of Ophthalmology, Norfolk and Norwich University Hospital, Norwich, UK.
John Van Geest Centre for Brain Repair, University of Cambridge, Cambridge, UK.
Eur J Ophthalmol. 2023 Sep;33(5):NP124-NP129. doi: 10.1177/11206721221118142. Epub 2022 Aug 7.
To report a case of recurrent acute retinal necrosis (ARN) in an eye filled with silicone oil previously complicated by rhegmatogenous retinal detachment (RRD).
A 68-year-old gentlemen with successfully treated herpes simplex virus type 1 (HSV1) ARN complicated by RRD requiring pars plana vitrectomy (PPV) with silicone oil tamponade, presented with a relapse of ARN with silicone oil in situ. Remission of recurrent retinitis was achieved using combined systemic oral and intravitreal antiviral therapy.
RRD is a significant complication of ARN which may require surgery with silicone oil tamponade. Recurrence of ARN retinitis can be effectively treated with intravitreal Ganciclovir and Foscarnet injections in a silicone oil filled eye with concurrent oral antiviral therapy. Aqueous humour sampling proved useful in the monitoring of disease activity.
报告 1 例硅油填充眼复发性急性视网膜坏死（ARN）病例，该病例先前并发孔源性视网膜脱离（RRD）。
1 例成功治疗单纯疱疹病毒 1 型（HSV1）ARN 合并 RRD 的 68 岁男性患者，需要行巩膜扣带术（PPV）联合硅油填充，该患者出现复发性 ARN 伴硅油在位。通过联合全身口服和玻璃体内抗病毒治疗，复发性视网膜炎缓解。
RRD 是 ARN 的严重并发症，可能需要手术联合硅油填充。在硅油填充眼，通过玻璃体内注射更昔洛韦和膦甲酸联合全身口服抗病毒治疗，可以有效治疗复发性 ARN 视网膜炎。眼内液样本的采集在监测疾病活动方面非常有用。
