Animal & Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Cork, Ireland.
Sheep Ireland, Highfield House, Shinagh, Bandon, Cork, Ireland.
Animal. 2022 Aug;16(8):100604. doi: 10.1016/j.animal.2022.100604. Epub 2022 Aug 5.
Monitoring the rate of change in inbreeding and genetic diversity within a population is important to guide breeding programmes. Such interest stems from the impact of loss in genetic diversity on sustainable genetic gain but also the impact on performance (i.e. inbreeding depression). The objective of the present study was to evaluate trends in inbreeding and genetic diversity in 43 066 Belclare, 120 753 Charollais, 22 652 Galway, 78 925 Suffolk, 187 395 Texel, and 19 821 Vendeen purebred sheep. The effective population size for each of the six breeds was between 116.0 (Belclare population) and 314.8 (Charollais population). The Charollais population was the most genetically diverse with the greatest number of effective founders, effective ancestors, and effective founder genomes; conversely, the Belclare was the least genetically diverse population with the fewest number of effective founders, effective ancestors, and effective founder genomes for each of the six breeds investigated. Overall, the effective population sizes and the total genetic diversity within each of the six breeds were above the minimum thresholds generally considered to be required for the long-term viability of a population.
监测群体内近交率和遗传多样性的变化速度对于指导育种计划非常重要。这种兴趣源于遗传多样性丧失对可持续遗传增益的影响，也源于对性能（即近交衰退）的影响。本研究的目的是评估 43,066 头贝克莱尔、120,753 头夏洛莱、22,652 头戈尔韦、78,925 头萨福克、187,395 头泰克塞尔和 19,821 头旺代纯种绵羊的近交和遗传多样性趋势。六个品种的有效群体大小分别为 116.0（贝克莱尔种群）至 314.8（夏洛莱种群）。夏洛莱种群遗传多样性最高，有效创始人、有效祖先和有效创始人基因组数量最多；相比之下，贝克莱尔种群遗传多样性最低，每个品种的有效创始人、有效祖先和有效创始人基因组数量最少。总体而言，六个品种的有效群体大小和每个品种的总遗传多样性均高于通常认为种群长期生存所需的最低阈值。
