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颈椎后路减压术治疗颈椎病性脊髓病的长期随访。

Long-Term Follow-Up After Cervical Laminectomy without Fusion for Cervical Spondylotic Myelopathy.

机构信息

Department of Neurosurgery, Helsinki University Hospital, Helsinki, Finland; Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Department of Radiology, Helsinki University Hospital, Helsinki, Finland.

出版信息

World Neurosurg. 2022 Nov;167:e222-e235. doi: 10.1016/j.wneu.2022.07.131. Epub 2022 Aug 6.

Abstract

OBJECTIVE

The objectives were to study the effect of cervical laminectomy without fusion on the incidence of further cervical surgeries, the risk for cervical misalignment, and current functional status.

METHODS

We retrospectively analyzed the clinical data of 340 patients who had undergone simple laminectomy for cervical spondylotic myelopathy (CSM) at Helsinki University Hospital between 2000 and 2011.

RESULTS

Forty-one patients (12.1%) had later undergone another cervical surgery during the follow-up of a mean of 8.5 years (maximum, 17.5 years). The most common indication for further surgery was residual stenosis at adjacent or other cervical levels (34%). Five patients (1%) required further surgery for correction of a sagittal balance problem. The mean Neck Disability Index was 28% at a median of 9.0 years after laminectomy. The mean EQ-5D (EuroQol 5 Dimension 3 Level) index score was 58.8 for patients and 77.2 for age-matched and gender-matched general population controls (P = 0.000), indicating patients' reduced health-related quality of life. Worse preoperative condition in the Nurick score was related to a lower (i.e., worse) EQ-5D score. In an additional arm of the study with radiographic imaging (40 patients), the mean change in sagittal alignment was 4.0° toward lordotic, and a newly developed kyphosis was found in 7.5% of patients.

CONCLUSIONS

Because CSM is a serious degenerative progressive condition resulting in decreased health-related quality of life even after surgical treatment, the low rate of corrective surgery needed for alignment issues per se indicates that simple laminectomy can be a viable treatment option in treating multilevel CSM.

摘要

目的

研究颈椎椎板切除术不融合对进一步颈椎手术的发生率、颈椎失稳的风险和当前功能状态的影响。

方法

我们回顾性分析了 2000 年至 2011 年期间在赫尔辛基大学医院接受单纯颈椎板切除术治疗颈椎病脊髓病(CSM)的 340 例患者的临床资料。

结果

在平均 8.5 年(最长 17.5 年)的随访中,有 41 例(12.1%)患者随后接受了另一项颈椎手术。进一步手术的最常见指征是相邻或其他颈椎水平的残余狭窄(34%)。有 5 例(1%)患者因矢状位平衡问题需要进一步手术矫正。在椎板切除术后中位数 9.0 年时,平均颈部残疾指数为 28%。患者的平均 EQ-5D(欧洲五维健康量表 3 级)指数评分为 58.8,年龄和性别匹配的一般人群对照组为 77.2(P<0.000),表明患者的健康相关生活质量下降。术前 Nurick 评分越差,EQ-5D 评分越低。在另一项影像学研究中(40 例患者),矢状面排列的平均变化为 4.0°向凸型,7.5%的患者发现新发生的后凸畸形。

结论

由于 CSM 是一种严重的退行性进行性疾病,即使经过手术治疗,健康相关生活质量也会下降,因此,为了矫正排列问题本身而需要的矫正手术率较低,表明单纯椎板切除术是治疗多节段 CSM 的一种可行的治疗选择。

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