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[心力衰竭家庭回归援助服务(PRADO-IC)对心力衰竭住院患者一年再住院率和死亡率的影响]

[Impact of Home Return Assistance Service in Heart Failure (PRADO-IC) on the one year re-hospitalisation and mortality in a heart failure hospitalized population of patients].

作者信息

Abassade Philippe, Cohen Léa, Fels Audrey, Chatellier Gilles, Sacco Emmanuelle, Beaussier Hélène, Fleury Laetitia, Komajda Michel, Cador Romain

机构信息

Service de Cardiologie, Groupe Hospitalier Paris Saint Joseph, 185 rue Raymond Losserand, 75014, Paris, France.

Service de Cardiologie, Groupe Hospitalier Paris Saint Joseph, 185 rue Raymond Losserand, 75014, Paris, France.

出版信息

Ann Cardiol Angeiol (Paris). 2022 Nov;71(5):267-275. doi: 10.1016/j.ancard.2022.07.004. Epub 2022 Aug 6.

Abstract

INTRODUCTION

Congestive heart failure (CHF) is associated with prolonged and recurrent hospitalizations; the prognosis remains poor. Since 2013, the Caisse Primaire d'Assurance Maladie (CPAM) has set up a support program PRADO-IC (support program for returning home after hospitalisation for heart failure). The aim of this study was to evaluate the impact of PRADO-IC on the heart failure readmission rate and death rate at one year.

METHODS

From September 2016 to September 2018, all patients hospitalized for heart failure at Saint-Joseph Hospital were included in an observational study. The inclusion in PRADO-IC program was at physician's discretion. Two groups were compared according to the inclusion in PRADO-IC or not (T). The primary endpoints were the comparison of one-year mortality and heart failure readmission rate between the two groups.

RESULTS

Six hundred and thirty-three patients were included, 262 in the PRADO-IC group and 371 in the non-PRADO group. Patients in the PRADO-IC cohort more frequently present severity criteria (age, weight, BNP level, arrhythmia, anemia, renal failure). Mortality at one year (19.5% vs 16.2%, p = 0.28) are equivalent in both groups. There were no significant differences in one-year rehospitalization rate for heart failure (HF) (35.1% in PRADO cohort vs 28% in T group, p = 0.06), the time to first hospitalization (74.5 days in PRADO vs 54.5 days in T, p = 0.55) and the length of hospitalization (6.0 days in PRADO vs 7.0 days in T, p = 0.29) between the two groups. Age, hyponatremia, anemia, cancer, HF re-hospitalization were variables linked to a risk of mortality, in a multivariable analysis.

CONCLUSION

Our study shows that the PRADO-IC program concerned to the most severe patients. Despite this, the one-year mortality and the HF readmission rate are similar between the two groups.

摘要

引言

充血性心力衰竭(CHF)与长期反复住院有关;预后仍然很差。自2013年以来,初级医疗保险基金(CPAM)设立了一项支持计划PRADO-IC(心力衰竭住院后回家支持计划)。本研究的目的是评估PRADO-IC对一年内心力衰竭再入院率和死亡率的影响。

方法

2016年9月至2018年9月,圣约瑟夫医院所有因心力衰竭住院的患者均纳入一项观察性研究。是否纳入PRADO-IC计划由医生自行决定。根据是否纳入PRADO-IC(T)将两组进行比较。主要终点是两组之间一年死亡率和心力衰竭再入院率的比较。

结果

共纳入633例患者,PRADO-IC组262例,非PRADO组371例。PRADO-IC队列中的患者更频繁地出现严重程度标准(年龄、体重、脑钠肽水平、心律失常、贫血、肾衰竭)。两组一年死亡率相当(19.5%对16.2%,p = 0.28)。两组在心力衰竭(HF)一年再入院率(PRADO队列中为35.1%,T组中为28%,p = 0.06)、首次住院时间(PRADO组为74.5天,T组为54.5天,p = 0.55)和住院时间(PRADO组为6.0天,T组为7.0天,p = 0.29)方面无显著差异。在多变量分析中,年龄、低钠血症、贫血、癌症、HF再住院是与死亡风险相关的变量。

结论

我们的研究表明,PRADO-IC计划涉及的是病情最严重的患者。尽管如此,两组之间的一年死亡率和HF再入院率相似。

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