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How to Optimize Rosacea Treatment for Better Patient Outcomes: An Opinion Piece.如何优化酒渣鼻治疗以获得更好的患者治疗效果:一篇观点文章。
J Clin Aesthet Dermatol. 2022 Jul;15(7):E60-E62.
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Long-term inflammatory rosacea management with subantibiotic dose oral doxycycline 40 mg modified-release capsules once daily.每日一次口服低剂量抗生素多西环素 40mg 缓释胶囊治疗长期炎症性酒渣鼻。
Dermatol Ther. 2022 Jan;35(1):e15180. doi: 10.1111/dth.15180. Epub 2021 Dec 2.
2
Rosacea treatment guideline for the Netherlands.荷兰酒渣鼻治疗指南。
Br J Dermatol. 2020 Jun;182(6):1504-1506. doi: 10.1111/bjd.18882. Epub 2020 Feb 20.
3
Recommendations for rosacea diagnosis, classification and management: update from the global ROSacea COnsensus 2019 panel.玫瑰痤疮诊断、分类和管理建议:2019 年全球玫瑰痤疮共识专家组更新。
Br J Dermatol. 2020 May;182(5):1269-1276. doi: 10.1111/bjd.18420. Epub 2019 Oct 16.
4
Update on the Management of Rosacea from the American Acne & Rosacea Society (AARS).美国痤疮与酒渣鼻协会(AARS)发布的酒渣鼻管理最新情况。
J Clin Aesthet Dermatol. 2019 Jun;12(6):17-24. Epub 2019 Jun 1.
5
A randomized phase 3b/4 study to evaluate concomitant use of topical ivermectin 1% cream and doxycycline 40-mg modified-release capsules, versus topical ivermectin 1% cream and placebo in the treatment of severe rosacea.一项评估伊维菌素 1%乳膏和多西环素 40mg 缓释胶囊与伊维菌素 1%乳膏和安慰剂联合治疗严重酒渣鼻的随机 3b/4 期研究。
J Am Acad Dermatol. 2020 Feb;82(2):336-343. doi: 10.1016/j.jaad.2019.05.063. Epub 2019 May 29.
6
Recent advances in understanding and managing rosacea.酒渣鼻认识与管理的最新进展
F1000Res. 2018 Dec 3;7. doi: 10.12688/f1000research.16537.1. eCollection 2018.
7
Efficacy and safety of oxymetazoline cream 1.0% for treatment of persistent facial erythema associated with rosacea: Findings from the 52-week open label REVEAL trial.1.0%盐酸奥洛他定乳膏治疗酒渣鼻相关持续性面部红斑的疗效和安全性:来自 52 周开放标签 REVEAL 试验的结果。
J Am Acad Dermatol. 2018 Jun;78(6):1156-1163. doi: 10.1016/j.jaad.2018.01.027. Epub 2018 Jan 31.
8
Defining treatment success in rosacea as 'clear' may provide multiple patient benefits: results of a pooled analysis.将酒渣鼻的治疗成功定义为“清除”可能会给患者带来多重益处:一项汇总分析的结果
J Dermatolog Treat. 2017 Aug;28(5):469-474. doi: 10.1080/09546634.2017.1343435. Epub 2017 Jul 4.
9
Physical modalities for the treatment of rosacea.治疗酒渣鼻的物理疗法。
J Dtsch Dermatol Ges. 2016 Dec;14 Suppl 6:38-43. doi: 10.1111/ddg.13144.
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A Tailored Approach to the Treatment of a Patient with a Severe Dynamic Manifestation of Rosacea: A Case Report.酒渣鼻严重动态表现患者的个体化治疗方法:病例报告
Drugs R D. 2016 Sep;16(3):279-283. doi: 10.1007/s40268-016-0141-0.

如何优化酒渣鼻治疗以获得更好的患者治疗效果:一篇观点文章。

How to Optimize Rosacea Treatment for Better Patient Outcomes: An Opinion Piece.

作者信息

Schaller Martin, Tan Jerry, Webster Guy

机构信息

Dr. Schaller is with the Department of Dermatology at Eberhard Karls University Tuebingen in Tuebingen, Baden-Wuerttemberg, Germany.

Dr. Tan is with the Windsor Clinical Research Inc and the Department of Medicine at University of Western Ontario in Windsor, Ontario, Canada.

出版信息

J Clin Aesthet Dermatol. 2022 Jul;15(7):E60-E62.

PMID:35942011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9345196/
Abstract

Rosacea is a chronic disease requiring long-term management. However, it is often treated according to package label instructions, which reflect the conditions of a Phase III study rather than a chronic disease. Furthermore, due to a lack of clinical data or guidelines on long-term treatment, many clinicians choose to discontinue treatment once success has been reached, rather than continuing with maintenance therapy. As experienced practicing dermatologists and investigators in the field, in this article we address the current evidence gaps in rosacea management and provide practical advice to clinicians on how optimal outcomes can be achieved and maintained in patients with rosacea in real-world practice, based on our own experience and the available clinical data.

摘要

酒渣鼻是一种需要长期管理的慢性疾病。然而,它通常是按照包装标签说明进行治疗的,这些说明反映的是III期研究的情况,而非慢性疾病的情况。此外,由于缺乏关于长期治疗的临床数据或指南,许多临床医生在病情好转后就选择停止治疗,而不是继续进行维持治疗。作为该领域经验丰富的执业皮肤科医生和研究人员,在本文中,我们将探讨酒渣鼻管理方面当前存在的证据空白,并根据我们自己的经验和现有的临床数据,为临床医生提供实用建议,说明在现实临床实践中如何实现并维持酒渣鼻患者的最佳治疗效果。