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REL-1017 (Esmethadone) May Rapidly Reduce Dissociative Symptoms in Adults With Major Depressive Disorder Unresponsive to Standard Antidepressants: A Report of 2 Cases.

作者信息

Guidetti Clotilde, Serra Giulia, Pani Luca, Pappagallo Marco, Maglio Gino, Trasolini Monia, De Martin Sara, Mattarei Andrea, Bifari Francesco, Folli Franco, Manfredi Paolo L, Fava Maurizio

出版信息

J Clin Psychopharmacol. 2022;42(5):503-506. doi: 10.1097/JCP.0000000000001583. Epub 2022 Aug 6.

DOI:10.1097/JCP.0000000000001583
PMID:35943402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9426728/
Abstract
摘要

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本文引用的文献

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Am J Psychiatry. 2022 Feb;179(2):122-131. doi: 10.1176/appi.ajp.2021.21020197. Epub 2021 Dec 22.
2
Prodromal Symptoms in Depression: A Systematic Review.抑郁前驱症状：系统综述。
Psychother Psychosom. 2021;90(6):365-372. doi: 10.1159/000517953. Epub 2021 Jul 20.
3
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program.在百万退伍军人计划中，创伤后应激障碍及其症状亚类的全基因组关联分析。
Nat Genet. 2021 Feb;53(2):174-184. doi: 10.1038/s41588-020-00767-x. Epub 2021 Jan 28.
4
A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder.一项重复使用氯胺酮治疗慢性创伤后应激障碍的随机对照试验。
Am J Psychiatry. 2021 Feb 1;178(2):193-202. doi: 10.1176/appi.ajp.2020.20050596. Epub 2021 Jan 5.
5
Characterization of the Safety and Pharmacokinetic Profile of D-Methadone, a Novel N-Methyl-D-Aspartate Receptor Antagonist in Healthy, Opioid-Naive Subjects: Results of Two Phase 1 Studies.健康、阿片类药物初治受试者中新型 N-甲基-D-天冬氨酸受体拮抗剂 D-美沙酮的安全性和药代动力学特征描述：两项 I 期研究结果。
J Clin Psychopharmacol. 2019 May/Jun;39(3):226-237. doi: 10.1097/JCP.0000000000001035.
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Dissociative Experience in Unipolar and Bipolar Depression: Exploring the Great Divide.单相和双相抑郁症中的解离体验：探索巨大差异
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