Khademi Behzad, Zia Zahra, Kohandel-Shirazi Mahsa
Department of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz, Iran.
Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
Ophthalmic Plast Reconstr Surg. 2023;39(1):e22-e25. doi: 10.1097/IOP.0000000000002258. Epub 2022 Aug 8.
Carcinoma ex pleomorphic adenoma (Ca ex PA) is defined as an infiltrative carcinoma arising from a primary or recurrent benign pleomorphic adenoma. Ca ex PA with the histologic subtype mucoepidermoid carcinoma is extremely uncommon. Only 2 previous reports in the lacrimal gland have been documented. We reported a 55-year-old lady with a firm, solid, nontender mass in the supralateral quadrant of the right orbit at the area of the lacrimal gland. After wide excision of mass, pathology revealed high-grade mucoepidermoid carcinoma Ex pleomorphic adenoma. To reduce tumor recurrence 60 Gray radiation was delivered to the orbital cavity. She is still tumor-free 1 year after completion of treatment.
多形性腺瘤恶变（Ca ex PA）被定义为起源于原发性或复发性良性多形性腺瘤的浸润性癌。具有黏液表皮样癌组织学亚型的Ca ex PA极为罕见。泪腺仅有2例既往报道。我们报告了一名55岁女性，在右眼眶泪腺区域的外上象限有一个质地硬、实性、无压痛的肿块。肿块广泛切除后，病理显示为高级别黏液表皮样癌伴多形性腺瘤恶变。为降低肿瘤复发率，对眼眶腔进行了60格雷的放疗。治疗完成1年后她仍无肿瘤复发。
