Song Ju-Ho, Bin Seong-Il, Kim Jong-Min, Lee Bum-Sik, Park Jun-Gu, Lee Sang-Min
Department of Orthopedic Surgery, Chungnam National University Sejong Hospital, Chungnam National University College of Medicine, Sejong, Republic of Korea.
Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Olympic-ro 43 gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Knee Surg Sports Traumatol Arthrosc. 2023 Feb;31(2):510-516. doi: 10.1007/s00167-022-07070-8. Epub 2022 Aug 9.
To evaluate the effect of age itself on the joint survivorship after arthroscopic partial meniscectomy (APM) for degenerative medial meniscus tears (DMTs).
Patients undergoing APM for DMTs during 1999-2010 were retrospectively reviewed. The inclusion criteria were as follows: (1) DMTs identified on preoperative MRI scans, (2) no definite history of trauma, and (3) follow-up duration more than 5 years. In evaluation of the joint survivorship, the endpoint was defined as conversion to arthroplasty (or realignment osteotomy) or progression to Kellgren-Lawrence grade 4. The study population was divided into older and younger groups by a cutoff age at which the difference in the joint survival rates was maximized, using a time-dependent receiver operating characteristic (ROC) curve. The two groups were then matched based on propensity scores. The joint survival rates were compared between the groups using Kaplan-Meier analysis, before and after propensity score matching (PSM).
A total of 633 knees were included. The cutoff age was calculated as 60 years. Before PSM, 239 knees were allocated to the older group (≥ 60 years) and 394 knees to the younger group (< 60 years). A significant difference in the joint survival rates was noted between the groups (log-rank test, p < 0.001). After PSM, 183 knees remained in each group. The difference in the survival rates was no more statistically significant (n.s.). The latest Lysholm scores of the older and the younger groups before PSM were 72.2 ± 20.8 and 79.9 ± 19.6, respectively (p < 0.001); however, the scores after PSM were 73.2 ± 20.3 and 77.4 ± 20.5, respectively (n.s.).
Joint survivorship after APM was affected by other factors associated with the aging process, such as cartilage status and meniscal tear pattern, rather than age itself. Advanced age should not be the only reason for precluding APM in treatment of DMTs. APM is a viable option when treating DMTs in elderly patients if adopted with caution. According to this study, a surgeon should assess the age-related factors when he considers APM in elderly patients.
III.
评估年龄本身对关节镜下部分半月板切除术(APM)治疗退行性内侧半月板撕裂(DMT)后关节生存率的影响。
对1999年至2010年期间接受APM治疗DMT的患者进行回顾性研究。纳入标准如下:(1)术前MRI扫描发现DMT;(2)无明确外伤史;(3)随访时间超过5年。在评估关节生存率时,终点定义为转为关节置换术(或截骨矫形术)或进展至Kellgren-Lawrence 4级。使用时间依赖性受试者工作特征(ROC)曲线,根据使关节生存率差异最大化的临界年龄将研究人群分为老年组和年轻组。然后根据倾向得分对两组进行匹配。在倾向得分匹配(PSM)前后,使用Kaplan-Meier分析比较两组的关节生存率。
共纳入633个膝关节。计算得出临界年龄为60岁。在PSM之前,239个膝关节被分配到老年组(≥60岁),394个膝关节被分配到年轻组(<60岁)。两组的关节生存率存在显著差异(对数秩检验,p<0.001)。PSM后,每组各有183个膝关节。生存率差异不再具有统计学意义(无显著性差异)。PSM前老年组和年轻组的最新Lysholm评分分别为72.2±20.8和79.9±19.6(p<0.001);然而,PSM后的评分分别为73.2±20.3和77.4±20.5(无显著性差异)。
APM后的关节生存率受与衰老过程相关的其他因素影响,如软骨状态和半月板撕裂模式,而非年龄本身。高龄不应是治疗DMT时排除APM的唯一原因。谨慎采用时,APM是治疗老年患者DMT的可行选择。根据本研究,外科医生在考虑对老年患者进行APM时应评估与年龄相关的因素。
III级