Department of Hospital Infection Control, University Clinical Centre Kragujevac, Kragujevac, Serbia.
Department of Clinical Pharmacology, University Clinical Centre of Kragujevac and Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Paediatr Int Child Health. 2022 May;42(2):59-66. doi: 10.1080/20469047.2022.2108672. Epub 2022 Aug 9.
Legionnaires' disease is an atypical pneumonia caused by inhaling small droplets of water containing the bacterium Legionella spp. In newborns, it is a rare event, usually associated with water births and the use of air conditioning systems or air humidifiers. A nosocomial outbreak of Legionnaires' disease in the maternity ward of a secondary-care hospital in Arandjelovac, Serbia is described.Two male newborns were found to be infected with . On Days 7 and 6 of life, respectively, they were transferred to a tertiary-care hospital with signs of severe pneumonia which was radiologically confirmed. was detected in tracheal secretions from both infants by RT-PCR, and its antigens were also positive in urine samples. The source of infection in the secondary-care hospital was the internal hot water heating system, and the main contributory factor to the emergence of the infection was the low temperature of the hot water which did not kill the bacteria during the available exposure time.These two cases highlight the importance of being cautious about possible Legionnaires' disease in maternity wards with outdated or irregularly maintained internal water supply systems. The adoption of official guidelines for the control and regular maintenance of water supply systems, including the multidisciplinary cooperation of all relevant parties, forms the basis for direct monitoring for Legionella and the prevention of new outbreaks. BCYE: buffered charcoal yeast extract agar; GVPC: glycine vancomycin polymyxin cycloheximide agar; LD - Legionnaires' disease; TR-PCR: Reverse transcription polymerase chain reaction.
军团病是一种由吸入含有军团菌属细菌的小水滴引起的非典型肺炎。在新生儿中，这是一种罕见的事件，通常与水中分娩以及使用空调系统或空气加湿器有关。本文描述了塞尔维亚阿南德耶沃市一家二级保健医院的妇产科发生的军团病暴发。发现两名男婴感染了。分别在第 7 天和第 6 天，他们因严重肺炎的迹象被转移到一家三级保健医院，该肺炎通过放射学确认。通过 RT-PCR 在两名婴儿的气管分泌物中均检测到 ，尿液样本中其抗原也呈阳性。二级保健医院的感染源是内部热水加热系统，感染出现的主要促成因素是热水温度低，在可用暴露时间内无法杀死细菌。这两个病例强调了在内部供水系统陈旧或维护不规律的妇产科病房中警惕可能发生军团病的重要性。采用控制和定期维护供水系统的官方指南，包括所有相关方的多学科合作，是直接监测军团菌和预防新暴发的基础。BCYE：缓冲炭酵母提取物琼脂；GVPC：甘氨酸万古霉素多粘菌素环丝氨酸琼脂；LD - 军团病；TR-PCR：逆转录聚合酶链反应。
