Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, MA, United States; Department of Endodontics, New York University College of Dentistry, New York, NY, United States.
Department of Cariology, Operative Dentistry and Dental Public Health, Indiana University School of Dentistry, Indianapolis, IN, United States.
Vaccine. 2022 Aug 26;40(36):5376-5383. doi: 10.1016/j.vaccine.2022.07.048. Epub 2022 Aug 6.
The incidence of HPV-related oropharyngeal and anal cancer has been increasing significantly over the past 30 years, especially among males. This study sought to better understand the level of knowledge of HPV-related disease in the LGBTQ+ community, and serve as a method to increase awareness for HPV vaccination as a safe and effective method for cancer prevention.
SCRUFF and Jack'd are geosocial networking and dating mobile applications for men who have sex with men (MSM). All users of the applications who were located in the US at the time of the study were invited to participate in a survey on HPV knowledge, the HPV vaccine, and vaccination status. The Pearson test was used to identify possible associations.
Half of the HPV vaccine-eligible respondents reported having received at least one dose of the HPV vaccine, while only 37.9% of the individuals aged 9-26 reported being vaccinated against HPV. Among the unvaccinated, 63.3% reported being interested in future vaccination, or learning more about it. No significant differences were noted regarding vaccination status nor HPV knowledge between respondents from rural vs urban locations. Respondents from the South were the least knowledgeable about cancer and genital warts caused by HPV (79.4%, p < 0.01), and had the lowest rate of vaccination compared to other regions (18.5%, p < 0.01). More than half of respondents reported being either somewhat comfortable (15.8%) or very comfortable (42.2%) with receiving the HPV vaccine from a dentist.
The findings of this study identify demographic groups and geographical areas where preventive campaigns for HPV would be most needed. The findings highlight dental providers as an underutilized source of HPV education and vaccine recommendation. The study reveals opportunities to close gaps in care and knowledge, and points to future directions for research and development of effective interventions.
在过去的 30 年中，HPV 相关的口咽和肛门癌的发病率显著上升，尤其是在男性中。本研究旨在更好地了解 LGBTQ+ 群体对 HPV 相关疾病的认知水平，并将 HPV 疫苗作为一种安全有效的癌症预防方法来提高认识。
SCRUFF 和 Jack'd 是面向男男性行为者的基于地理位置的社交网络和约会移动应用程序。研究时位于美国的应用程序的所有用户都被邀请参加一项关于 HPV 知识、HPV 疫苗和疫苗接种状况的调查。使用 Pearson 检验来确定可能的关联。
半数 HPV 疫苗合格的受访者报告至少接种过一剂 HPV 疫苗，而仅 37.9%的 9-26 岁个体接种了 HPV 疫苗。在未接种疫苗的人群中，63.3%的人表示有兴趣在未来接种疫苗或更多地了解它。来自农村地区与城市地区的受访者在疫苗接种状况和 HPV 知识方面没有显著差异。来自南部的受访者对 HPV 引起的癌症和生殖器疣了解最少（79.4%，p<0.01），与其他地区相比，接种率最低（18.5%，p<0.01）。超过一半的受访者表示，他们对从牙医那里接种 HPV 疫苗感到有些（15.8%）或非常（42.2%）舒服。
本研究的结果确定了需要进行 HPV 预防活动的人口群体和地理区域。研究结果强调了牙医作为 HPV 教育和疫苗推荐的未充分利用的资源。该研究揭示了缩小护理和知识差距的机会，并为未来的研究和开发有效的干预措施指明了方向。
