Department of Physical Medicine and Rehabilitation, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.
Department of Physical Medicine and Rehabilitation, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
J Orthop Sci. 2023 Sep;28(5):1004-1010. doi: 10.1016/j.jos.2022.07.001. Epub 2022 Aug 6.
Shoulder disorders, including frozen shoulder, bursitis, and rotator cuff lesions, are common musculoskeletal problems in patients with Parkinson disease (PD). Because musculoskeletal ultrasound (US) can clearly image shoulder joints, we aimed to evaluate shoulder joints using US in patients with PD and healthy participants and correlation between US and PD severity.
This is a prospective case-control study. 50 patients with PD and 50 healthy subjects from the outpatient department were administered US for bilateral shoulders. For data analysis, we chose the more severely affected side in the PD group for matching with the corresponding shoulder in the control group according to age, sex, and body mass index. Pain and disability were measured using the Visual Analogue Scale (VAS) for pain, Shoulder Pain and Disability Index (SPADI), and the Shoulder Disability Questionnaire (SDQ).
The PD group had higher VAS pain scores during activity (p = 0.003) and rest (p < 0.001), as well as the SPADI and SDQ scores (p < 0.001). In US findings, biceps long head tendon sheath effusion (p = 0.001), humeral head cortical irregularity (p = 0.012), and abnormality in the supraspinatus tendon (p = 0.003) were significantly greater in the PD group. Intra-group analysis in the PD group demonstrated a significant difference in passive flexion (p = 0.019) and supraspinatus tendinopathy (p = 0.033) on US examination during different disease stages.
Patients with PD had more supraspinatus tendinopathy on US findings than control subjects. The lesion was significantly associated with disease severity.
NCT02702232.
肩部疾病，包括冻结肩、滑囊炎和肩袖损伤，是帕金森病（PD）患者常见的肌肉骨骼问题。由于肌肉骨骼超声（US）可以清晰地成像肩部关节，我们旨在使用 US 评估 PD 患者和健康参与者的肩部关节，并评估 US 与 PD 严重程度的相关性。
这是一项前瞻性病例对照研究。我们对来自门诊的 50 名 PD 患者和 50 名健康对照者进行了双侧肩部 US 检查。为了数据分析，我们根据年龄、性别和体重指数，选择 PD 组中更严重的一侧与对照组中相应的肩部进行匹配。疼痛和残疾采用视觉模拟评分（VAS）评估疼痛、肩痛和残疾指数（SPADI）和肩功能障碍问卷（SDQ）评估。
PD 组在活动时（p=0.003）和休息时（p<0.001）的 VAS 疼痛评分、SPADI 和 SDQ 评分更高（p<0.001）。在 US 发现中，肱二头肌长头肌腱鞘积液（p=0.001）、肱骨头皮质不规则（p=0.012）和冈上肌腱异常（p=0.003）在 PD 组中更为显著。PD 组的组内分析显示，在不同疾病阶段的 US 检查中，被动屈曲（p=0.019）和冈上肌腱病变（p=0.033）有显著差异。
PD 患者的 US 发现中冈上肌腱病变比对照组更常见。该病变与疾病严重程度显著相关。
NCT02702232。
