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一例罕见的乳糜泻合并大脑静脉窦血栓形成病例。

An Uncommon Case of Celiac Disease and Deep Cerebral Venous Sinus Thrombosis.

作者信息

Singla Monika, Singh Balveen, Midha Vandana, Paul Birinder S

机构信息

Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.

出版信息

J Neurosci Rural Pract. 2022 Jun 23;13(3):568-570. doi: 10.1055/s-0042-1749458. eCollection 2022 Jul.

Abstract

Celiac disease is an enteropathy characterized by malabsorption related with gluten intolerance and immune-mediated pathogenesis. It may manifest with gastrointestinal features like diarrhea, abdominal pain, weight loss, and anemia. Besides, it can manifest with various extraintestinal features like ataxia, neuropathy, stroke, or sometimes venous sinus thrombosis. Being of autoimmune origin, relation with systemic lupus erythematosus has also been reported. Herein, we present a rare case of a young patient with celiac disease who presented with fever, headache, and altered sensorium and was found to have meningitis with deep cerebral venous sinus thrombosis.

摘要

乳糜泻是一种以与麸质不耐受和免疫介导的发病机制相关的吸收不良为特征的肠病。它可能表现为胃肠道症状,如腹泻、腹痛、体重减轻和贫血。此外,它还可能表现为各种肠外症状,如共济失调、神经病变、中风,或有时出现静脉窦血栓形成。由于其自身免疫起源,也有与系统性红斑狼疮相关的报道。在此,我们报告一例罕见的年轻乳糜泻患者,该患者出现发热、头痛和意识改变,被发现患有脑膜炎并伴有大脑深静脉窦血栓形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/950d/9357487/bfeb94a05da8/10-1055-s-0042-1749458-i21122278-1.jpg

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