Suresh Sapna, Hrishi Ajay Prasad, Divakar Ganesh, Sethuraman Manikandan
Department of Neuroanesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
J Neurosci Rural Pract. 2022 Jun 13;13(3):563-567. doi: 10.1055/s-0042-1749457. eCollection 2022 Jul.
Metastatic pheochromocytoma (PCC) is a rare entity arising from extra-adrenal tissue. We report the perioperative management of a young woman presenting with metastatic PCC to the vertebral body resulting in vertebral collapse and spinal cord compression necessitating emergency surgery. There are no reports of anesthetic management of a patient with unoptimized metastatic PCC presenting for emergency neurosurgery under general anesthesia. Our anesthetic goals were to maintain a deep anesthetic plane with stable hemodynamics, facilitate intraoperative neuromonitoring, manage catecholamine surges during anesthetic induction, tumor resection, and manage perioperative massive blood loss. The successful perioperative management of metastatic PCC has become possible with the vast armamentarium of anesthetic drugs and intraoperative advanced monitoring techniques. In addition, our role in understanding the pathophysiology and course of the disease is essential to ensure low morbidity and mortality of such cases in their most vulnerable perioperative period.
转移性嗜铬细胞瘤(PCC)是一种起源于肾上腺外组织的罕见疾病。我们报告了一名年轻女性的围手术期管理情况,该患者患有转移性PCC,肿瘤转移至椎体导致椎体塌陷和脊髓受压,因此需要进行急诊手术。目前尚无关于在全身麻醉下为未优化的转移性PCC患者进行急诊神经外科手术的麻醉管理报告。我们的麻醉目标是维持深度麻醉平面并保持血流动力学稳定,促进术中神经监测,处理麻醉诱导、肿瘤切除过程中的儿茶酚胺激增情况,并应对围手术期大量失血。随着大量麻醉药物和术中先进监测技术的出现,转移性PCC的围手术期成功管理已成为可能。此外,我们了解疾病病理生理学和病程的作用对于确保此类病例在最脆弱的围手术期实现低发病率和死亡率至关重要。