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抗-Koch 治疗致结核患者抗磷脂酶 A2 受体抗体阳性膜性肾小球病。

Anti-phospholipase A2 Receptor Antibody-Positive Membranous Glomerulopathy due to Anti-Koch's Therapy in a Tuberculosis Patient.

机构信息

Department of Nephrology, Jawaharlal Nehru Medical College, Sawangi, Wardha; Department of Nephrology, Saraswati Kidney Care Center, Nagpur, Maharashtra, India.

Department of Nephrology, All India Institute of Medical Sciences, Nagpur, Maharashtra, India.

出版信息

Saudi J Kidney Dis Transpl. 2021 Nov-Dec;32(6):1800-1803. doi: 10.4103/1319-2442.352444.

Abstract

Tuberculosis (TB)-associated glomerulonephritis is difficult to diagnose that usually presents with hematuria, proteinuria, edema, hypertension, or renal insufficiency, which is similar to symptoms of primary glomerulonephritis. Membranous nephropathy (MN) is uncommonly seen in TB patients. We report a case of a 30-year-old female with Koch's chest who developed anti-phospholipase A2 receptor antibody-positive MN after initiation of anti-Koch's therapy and resolved after completion of anti-Koch's therapy.

摘要

结核相关肾小球肾炎的诊断较为困难,其临床表现通常为血尿、蛋白尿、水肿、高血压或肾功能不全,与原发性肾小球肾炎的症状相似。膜性肾病在结核患者中并不常见。我们报告了一例 30 岁女性患者,其患有科赫氏胸,在开始抗科赫氏治疗后发生抗磷脂酶 A2 受体抗体阳性的膜性肾病,在完成抗科赫氏治疗后缓解。

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