与小蚀斑变异体相关的基孔肯雅病毒体内自身干扰
Chikungunya virus in vivo autointerference associated with a small plaque variant.
作者信息
Chanas A C, Johnson B K, Simpson D I
出版信息
Acta Virol. 1978 Nov;22(6):485-90.
PMID:35947
Abstract
Virulent and avirulent plaque variants of Chikungunya (CHIK) virus were compared with the prototype and other strains. Interference with infective virus growth or mouse pathogenicity only occurred in the presence of small plaque (SP) variants in homologous systems. Possible mechanisms for this are suggested.
摘要
将基孔肯雅病毒（CHIK）的强毒株和无毒株菌斑变体与原型株及其他毒株进行了比较。仅在同源系统中存在小菌斑（SP）变体时，才会出现对感染性病毒生长或小鼠致病性的干扰。文中提出了对此现象的可能机制。
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