J Refract Surg. 2022 Aug;38(8):480-486. doi: 10.3928/1081597X-20220609-01. Epub 2022 Aug 1.
To evaluate the predictors related to the efficacy of epithelium- and Bowman membrane-penetrating femtosecond laser-assisted arcuate keratotomy (FSAK) in the treatment of preoperative astigmatism in patients with cataracts and to clarify the predictive role of the incision-to-limbus distance.
This retrospective study included patients who underwent femtosecond laser-assisted cataract surgery combined with FSAK using the LenSX platform (Alcon Laboratories, Inc) at Beijing Aier-Intech Eye Hospital from March 2017 to December 2021. The Lenstar LS900 (Haag-Streit, Inc) was used to measure the horizontal corneal diameter, and ImageJ software (National Institutes of Health) was used to measure the vertical corneal diameter and incision-to-limbus distance. Finally, the measured values were converted. Changes in corneal astigmatism before and 3 months after surgery were analyzed using Alpins vector analysis. Correlation analysis and regression analysis were used to evaluate the factors associated with surgically induced astigmatism (SIA) in preoperative ocular biometric parameters.
The study included 94 eyes of 94 patients. The mean target induced astigmatism was 1.36 ± 0.44 diopters (D), SIA was 0.82 ± 0.43 D, and mean difference vector was 0.70 ± 0.40 D. Pearson correlation analysis and univariate regression analysis showed that preoperative corneal astigmatism, arcuate keratotomy arc length, incision-to-limbus distance, and astigmatism type were significant predictors of SIA. Multiple variable regression analysis included parameters such as age, arcuate keratotomy arc length, and incision-to-limbus distance and established a multiple regression model of SIA (all < .01).
The incision-to-limbus distance was a significant independent predictor of SIA, and inclusion of this parameter may further improve the accuracy of the nomogram. .
评估与白内障术前散光患者行飞秒激光辅助弧形角膜切开术(FSAK)治疗相关的疗效预测因子,并阐明切口至角膜缘距离的预测作用。
本回顾性研究纳入 2017 年 3 月至 2021 年 12 月在北京爱尔英智眼科医院接受 LenSX 平台(爱尔康公司)辅助飞秒激光白内障手术联合 FSAK 的患者。采用 Lenstar LS900(哈格斯特赖希公司)测量水平角膜直径,使用 ImageJ 软件(美国国立卫生研究院)测量垂直角膜直径和切口至角膜缘距离。最后将测量值进行转换。使用 Alpins 向量分析法分析手术前后角膜散光的变化。采用相关分析和回归分析评估术前眼生物测量参数与手术诱导散光(SIA)相关的因素。
研究共纳入 94 例(94 只眼)患者。平均目标诱导散光为 1.36±0.44 屈光度(D),SIA 为 0.82±0.43 D,平均差异向量为 0.70±0.40 D。Pearson 相关分析和单变量回归分析显示,术前角膜散光、弧形角膜切开弧长、切口至角膜缘距离和散光类型是 SIA 的显著预测因子。多元变量回归分析纳入年龄、弧形角膜切开弧长和切口至角膜缘距离等参数,建立了 SIA 的多元回归模型(均 <.01)。
切口至角膜缘距离是 SIA 的显著独立预测因子,纳入该参数可能进一步提高列线图的准确性。