School of Nursing, Yale University, New Haven, CT, USA.
Center for Interdisciplinary Research on AIDS, School of Public Health, Yale University, New Haven, CT, USA.
AIDS Behav. 2023 May;27(Suppl 1):128-143. doi: 10.1007/s10461-022-03776-5. Epub 2022 Aug 10.
Adolescents and sexual minority men (SMM) are high priority groups in the United Nations' 2021 - 2016 goals for HIV prevention and viral load suppression. Interventions aimed at optimizing HIV prevention, testing and viral load suppression for adolescents must also attend to the intersectional realities influencing key sub-populations of SMM. Consequently, there is not a robust evidence-base to guide researchers and program partners on optimal approaches to implementing interventions with adolescent SMM. Using a multiple case study design, we integrated the Implementation Research Logic Model with components of the Consolidated Framework for Implementation Research and applied it as a framework for a comparative description of ten HIV related interventions implemented across five countries (Ghana, Kenya, Nigeria, Tanzania and United States). Using self-reported qualitative survey data of project principal investigators, we identified 17 of the most influential implementation determinants as well as a range of 17 strategies that were used in 90 instances to support intervention implementation. We highlight lessons learned in the implementation research process and provide recommendations for researchers considering future HIV implementation science studies with adolescent SMM.
青少年和性少数群体男性（SMM）是联合国 2021-2016 年艾滋病毒预防和病毒载量抑制目标的重点群体。旨在优化青少年艾滋病毒预防、检测和病毒载量抑制的干预措施，也必须关注影响 SMM 主要亚群体的交叉现实情况。因此，没有一个强大的证据基础来指导研究人员和项目合作伙伴采取最佳方法，用青少年 SMM 实施干预措施。本研究采用多案例研究设计，将实施研究逻辑模型与实施研究综合框架的组成部分相结合，并将其作为框架，对在五个国家（加纳、肯尼亚、尼日利亚、坦桑尼亚和美国）实施的十项艾滋病毒相关干预措施进行比较描述。研究人员利用项目主要研究者的自我报告定性调查数据，确定了 17 个最具影响力的实施决定因素，以及在 90 次情况下用于支持干预实施的一系列 17 种策略。研究人员还强调了实施研究过程中的经验教训，并为考虑未来用青少年 SMM 开展艾滋病毒实施科学研究的研究人员提供了建议。
