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内镜超声引导下经胃逆行胰胆管造影术(EDGE)在介入内镜医师中的应用趋势

Endoscopic Ultrasound-Directed Transgastric ERCP (EDGE) Utilization of Trends Among Interventional Endoscopists.

作者信息

Shah-Khan Sardar M, Zhao Eric, Tyberg Amy, Sarkar Sardar, Shahid Haroon M, Duarte-Chavez Rodrigo, Gaidhane Monica, Kahaleh Michel

机构信息

Department of Gastroenterology, Rutgers Robert Wood Johnson Medical School, Robert Wood Johnson University Hospital, New Brunswick, NJ, 08901, USA.

出版信息

Dig Dis Sci. 2023 Apr;68(4):1167-1177. doi: 10.1007/s10620-022-07650-1. Epub 2022 Aug 10.

Abstract

BACKGROUND

Endoscopic ultrasound-directed transgastric ERCP (EDGE) has become standard-of-care therapy at many centers for pancreaticobiliary disease in patients with Roux-en-Y Gastric Bypass. In this study, we aimed to evaluate the opinions and practices of endoscopists who perform EDGE.

METHODS

A 22-question utilization of EDGE survey was sent to 36 advanced endoscopists at tertiary care centers in the United States. The two-section survey included questions regarding advanced endoscopy volume and training at the respective facilities, and questions on specific details of EDGE utilization.

RESULTS

Among 36 interventional endoscopists (IE) surveyed, 14 (39%) reported performing > 1000 ERCPs annually. Thirty (83%) offered EDGE as an option for Roux-en-Y gastric bypass patients with previous cholecystectomy. Other options offered included: 19 (53%) offered Laparoscopy-assisted ERCP (LA-ERCP), 7 (19%) offered Single-Balloon ERCP (SBE), and 10 (28%) offered percutaneous drainage (PTC). Twenty (56%) IE performed 10 or less EDGE procedures, while 16 (44%) performed 11 or more. Single-session EDGE was performed by 7 (19%) IE, while 15 (42%) performed dual session, and 13 (36%) performed both. 19 (53%) actively closed fistulas while 17 (47%) let them close spontaneously. Thirty one (86%) reported a technical success rate of 91% to 100%. The most frequently reported immediate adverse event post-procedurally was abdominal pain, reported by 17 IE (47%). Weight gain was reported by 2 IE (6%).

CONCLUSION

EDGE continues to gain in popularity as an option for Roux-en-Y gastric bypass patients requiring pancreaticobiliary interventions, with 24/36 IE (67%) believing that it should be the new standard. In addition, most report a low frequency of post-procedural weight gain.

CLINICAL TRIAL REGISTRATION

ClinicalTrials.gov Identifier NCT05041608.

摘要

背景

内镜超声引导下经胃逆行胰胆管造影术(EDGE)已成为许多中心治疗接受 Roux-en-Y 胃旁路手术患者胰胆疾病的标准治疗方法。在本研究中,我们旨在评估实施 EDGE 的内镜医师的观点和实践。

方法

向美国三级医疗中心的 36 名高级内镜医师发送了一份关于 EDGE 使用情况的 22 个问题的调查问卷。这份两部分的调查问卷包括有关各自机构高级内镜检查量和培训的问题,以及关于 EDGE 使用具体细节的问题。

结果

在接受调查的 36 名介入内镜医师(IE)中,14 名(39%)报告每年进行超过 1000 例逆行胰胆管造影术(ERCP)。30 名(83%)为接受过胆囊切除术的 Roux-en-Y 胃旁路手术患者提供 EDGE 作为一种选择。提供的其他选择包括:19 名(53%)提供腹腔镜辅助 ERCP(LA-ERCP),7 名(19%)提供单气囊 ERCP(SBE),10 名(28%)提供经皮引流(PTC)。20 名(56%)IE 进行 10 例或更少的 EDGE 手术,而 16 名(44%)进行 11 例或更多。7 名(19%)IE 进行单期 EDGE,15 名(42%)进行两期,13 名(36%)两者都进行。19 名(53%)积极封闭瘘管,而 17 名(47%)让其自行封闭。31 名(86%)报告技术成功率为 91%至 100%。术后最常报告的即刻不良事件是腹痛,17 名 IE(47%)报告。2 名 IE(6%)报告体重增加。

结论

对于需要胰胆干预的 Roux-en-Y 胃旁路手术患者,EDGE 作为一种选择越来越受欢迎,36 名 IE 中有 24 名(67%)认为它应该成为新标准。此外,大多数人报告术后体重增加的频率较低。

临床试验注册

ClinicalTrials.gov 标识符 NCT05041608。

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