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经口内镜下肌切开术(POEM)治疗食管动力障碍。

Peroral Endoscopy Myotomy (POEM) for Esophageal Motility Disorders.

机构信息

Department of Medicine, Feinberg School of Medicine, Northwestern University, 251 E Huron St, 60611, Chicago, IL, USA.

Division of Gastroenterology and Hepatology, Banner University Medical Center, University of Arizona, Tucson, AZ, USA.

出版信息

Curr Gastroenterol Rep. 2022 Sep;24(9):105-114. doi: 10.1007/s11894-022-00845-6. Epub 2022 Aug 10.

Abstract

PURPOSE OF REVIEW

This review aims to provide an overview of the current role of per oral endoscopic myotomy (POEM) in the management of primary esophageal motility disorders and treatment of Zenker's diverticulum.

RECENT FINDINGS

POEM has been shown to be an effective treatment for achalasia. Recent research has suggested that the length of myotomy may be tailored to the disease phenotype and that short myotomy may be equally effective compared to long myotomy. The role of intra-operative EndoFLIP has shown promise as a tool to assess of the adequacy of myotomy. Further research is needed to determine the role of POEM in other esophageal motility disorders and for treatment of Zenker's diverticulum. Per oral endoscopic myotomy has been shown to be an effective and durable treatment option for achalasia with additional potential roles for the treatment of other esophageal motility disorders and Zenker's diverticulum.

摘要

目的综述

本文旨在概述经口内镜下肌切开术(POEM)在原发性食管动力障碍的管理和Zenker 憩室治疗中的作用。

最近的发现

POEM 已被证明是治疗贲门失弛缓症的有效方法。最近的研究表明,肌切开的长度可以根据疾病表型进行调整,短肌切开与长肌切开同样有效。术中 EndoFLIP 的应用显示出作为评估肌切开术充分性的一种工具的潜力。需要进一步的研究来确定 POEM 在其他食管动力障碍和 Zenker 憩室治疗中的作用。POEM 已被证明是贲门失弛缓症的一种有效且持久的治疗选择,对于治疗其他食管动力障碍和 Zenker 憩室也具有潜在作用。

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