Real-Time, Nondestructive Optical Feedback Systems for Infrared Laser Sealing of Blood Vessels.

High-power infrared (IR) diode lasers are capable of sealing blood vessels during surgery. This study characterizes an optical feedback system for real-time, nondestructive identification of vessel seals. A low power, red aiming beam (635 nm) was used for diagnostics, co-aligned with a therapeutic high-power IR beam (1470 nm). The IR laser delivered either 30 W for 5 s for successful seals or 5 W for 5 s for unsuccessful seals (control). All studies used a linear beam measuring 8.4 × 2.0 mm. Optical signals for successful and failed seals were correlated with vessel burst pressures (BP) using destructive testing via a standard BP setup. Light scattering increased significantly as vessels were coagulated. Successful seals correlated with a percent decrease in optical transmission signal of 59 ± 11 % and seal failures to a transmission decrease of 23 ± 8% (p < 0.01). With further development, the real-time optical feedback system may be integrated into a laparoscopic device to de-activate the laser upon successful vessel sealing.