Giglio Nicholas C, Fried Nathaniel M
Department of Physics and Optical Science, University of North Carolina at Charlotte, NC.
Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb;11936. doi: 10.1117/12.2605600. Epub 2022 Mar 3.
High-power infrared (IR) diode lasers are capable of sealing blood vessels during surgery. This study characterizes an optical feedback system for real-time, nondestructive identification of vessel seals. A low power, red aiming beam (635 nm) was used for diagnostics, co-aligned with a therapeutic high-power IR beam (1470 nm). The IR laser delivered either 30 W for 5 s for successful seals or 5 W for 5 s for unsuccessful seals (control). All studies used a linear beam measuring 8.4 × 2.0 mm. Optical signals for successful and failed seals were correlated with vessel burst pressures (BP) using destructive testing via a standard BP setup. Light scattering increased significantly as vessels were coagulated. Successful seals correlated with a percent decrease in optical transmission signal of 59 ± 11 % and seal failures to a transmission decrease of 23 ± 8% (p < 0.01). With further development, the real-time optical feedback system may be integrated into a laparoscopic device to de-activate the laser upon successful vessel sealing.
高功率红外（IR）二极管激光器能够在手术过程中封闭血管。本研究对一种用于实时、无损识别血管封闭情况的光学反馈系统进行了特性描述。使用低功率红色瞄准光束（635纳米）进行诊断，该光束与治疗用高功率红外光束（1470纳米）共轴对准。对于成功的血管封闭，红外激光以30瓦功率照射5秒；对于不成功的血管封闭（对照），则以5瓦功率照射5秒。所有研究均使用尺寸为8.4×2.0毫米的线性光束。通过标准的血压设置进行破坏性测试，将成功和失败的血管封闭的光信号与血管破裂压力（BP）相关联。随着血管凝固，光散射显著增加。成功的血管封闭与光传输信号降低59±11%相关，而血管封闭失败与光传输降低23±8%相关（p<0.01）。随着进一步发展，实时光学反馈系统可集成到腹腔镜设备中，以便在成功封闭血管后关闭激光。
