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一例罕见的阑尾憩室纤维性闭塞偶然发现病例。

A Case of a Rare, Incidental Discovery of Fibrous Obliteration of an Appendiceal Diverticulum.

作者信息

Jenkins Joshua K, Morrow Colton A, Chaudhary Shweta, Brashear Jeffery H

机构信息

Research, Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Harrogate, USA.

Pathology, Hazard Appalachian Regional Healthcare (ARH) Regional Medical Center, Hazard, USA.

出版信息

Cureus. 2022 Jul 9;14(7):e26681. doi: 10.7759/cureus.26681. eCollection 2022 Jul.

Abstract

Diverticulosis of the appendix (DA) is rare and frequently found incidentally. Some cases are discovered after presenting with similar symptomatology to acute appendicitis, whereas other cases may be completely silent. Fibrous obliteration (FO) is a histologic finding indicative of cellular proliferation secondary to relapses of subclinical inflammatory processes. We report a case of a 75-year-old female with a history of chronic, intermittent abdominal pains who presented to the general surgery clinic after an abnormal thickening of the appendix was discovered on abdominal and pelvic computed tomography imaging. The patient underwent laparoscopic appendectomy for suspicion of malignancy. The histologic evaluation of the specimen demonstrated a diverticulum at the distal end of the appendix with FO of the lumen. We suspect the chronic nature of her disease course may have led to the FO of the diverticulum. An extensive literature search was performed, which revealed no other cases of FO of appendiceal diverticula. This may be the first case of diverticulosis of the appendix with FO in the English medical literature. If DA is discovered early with non-invasive imaging, surgical excision should be performed prophylactically as an association with an increased risk of perforation and neoplastic progression has been found.

摘要

阑尾憩室病(DA)较为罕见,常为偶然发现。部分病例在出现与急性阑尾炎相似的症状后被发现,而其他病例可能毫无症状。纤维性闭塞(FO)是一种组织学表现,提示亚临床炎症过程复发继发的细胞增殖。我们报告一例75岁女性,有慢性间歇性腹痛病史,在腹部和盆腔计算机断层扫描成像发现阑尾异常增厚后到普通外科门诊就诊。患者因怀疑恶性肿瘤接受了腹腔镜阑尾切除术。标本的组织学评估显示阑尾远端有一个憩室,管腔存在纤维性闭塞。我们怀疑其病程的慢性性质可能导致了憩室的纤维性闭塞。进行了广泛的文献检索,未发现其他阑尾憩室纤维性闭塞的病例。这可能是英文医学文献中首例伴有纤维性闭塞的阑尾憩室病。如果通过非侵入性成像早期发现DA,鉴于已发现其与穿孔和肿瘤进展风险增加有关,应进行预防性手术切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2451/9358985/baa403d23d23/cureus-0014-00000026681-i01.jpg

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