• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

食管胃交界部神经内分泌肿瘤合并腺癌：一例报告。

Esophagogastric junctional neuroendocrine tumor with adenocarcinoma: A case report.

作者信息

Kong Zhen-Zhen, Zhang Lu

机构信息

Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310000, Zhejiang Province, China.

出版信息

World J Clin Cases. 2022 Jun 26;10(18):6241-6246. doi: 10.12998/wjcc.v10.i18.6241.

DOI:10.12998/wjcc.v10.i18.6241
PMID:35949855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9254174/
Abstract

BACKGROUND

At present, cases of esophageal neuroendocrine tumors combined with cardia adenocarcinoma are extremely rare worldwide, and there are no clinical reports. Herein, we describe such a case for clinical reference.

CASE SUMMARY

The presence of cardia cancer and esophageal neuroendocrine tumors in a single patient has not yet been reported. The patient in this case underwent prompt endoscopic treatment and additional surgical resection. Pathology revealed the following: The distance between the cardia cancer and the esophageal neuroendocrine tumors was small, approximately 3 mm. Vascular invasion was observed. The esophageal neuroendocrine tumor was determined to be grade G3. According to the treatment guidelines, after the patient received an explanation of their condition, additional surgical procedures were provided in a timely manner. Early detection and early treatment can successfully prolong survival and improve the quality of life of patients.

CONCLUSION

Early detection and early treatment can successfully prolong survival and improve the quality of life of such patients.

摘要

背景

目前，食管神经内分泌肿瘤合并贲门腺癌的病例在全球极为罕见，尚无临床报道。在此，我们描述这样一例病例以供临床参考。

病例摘要

同一患者同时存在贲门癌和食管神经内分泌肿瘤的情况尚未见报道。本例患者接受了及时的内镜治疗及额外的手术切除。病理结果如下：贲门癌与食管神经内分泌肿瘤之间的距离较小，约3毫米。观察到血管侵犯。食管神经内分泌肿瘤被判定为G3级。根据治疗指南，在向患者解释病情后，及时进行了额外的手术。早期发现和早期治疗可成功延长患者生存期并提高生活质量。

结论

早期发现和早期治疗可成功延长此类患者的生存期并提高生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/8b3526a4d068/WJCC-10-6241-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/3cf9432bbdea/WJCC-10-6241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/fccbd3f87ac9/WJCC-10-6241-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/84fb15fc0858/WJCC-10-6241-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/a6099551513e/WJCC-10-6241-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/ad60776bd607/WJCC-10-6241-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/8b3526a4d068/WJCC-10-6241-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/3cf9432bbdea/WJCC-10-6241-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/fccbd3f87ac9/WJCC-10-6241-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/84fb15fc0858/WJCC-10-6241-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/a6099551513e/WJCC-10-6241-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/ad60776bd607/WJCC-10-6241-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d65/9254174/8b3526a4d068/WJCC-10-6241-g006.jpg

相似文献

1
Esophagogastric junctional neuroendocrine tumor with adenocarcinoma: A case report.食管胃交界部神经内分泌肿瘤合并腺癌：一例报告。
World J Clin Cases. 2022 Jun 26;10(18):6241-6246. doi: 10.12998/wjcc.v10.i18.6241.
2
Esophageal intramural metastasis from an adenocarcinoma of the gastric cardia: report of a case.胃贲门腺癌的食管壁内转移：一例报告
Surg Today. 1998;28(11):1160-2. doi: 10.1007/s005950050304.
3
Outcomes of endoscopic submucosal dissection for early esophageal and gastric cardia adenocarcinomas.早期食管及贲门腺癌内镜黏膜下剥离术的治疗结果
Clin Res Hepatol Gastroenterol. 2021 May;45(3):101700. doi: 10.1016/j.clinre.2021.101700. Epub 2021 Apr 20.
4
AGA Clinical Practice Update on Endoscopic Treatment of Barrett's Esophagus With Dysplasia and/or Early Cancer: Expert Review.AGA 临床实践更新：内镜治疗伴异型增生和/或早期癌症的 Barrett 食管：专家综述。
Gastroenterology. 2020 Feb;158(3):760-769. doi: 10.1053/j.gastro.2019.09.051. Epub 2019 Nov 12.
5
Clinicopathological features of Siewert type II adenocarcinoma: comparison of gastric cardia adenocarcinoma and Barrett's esophageal adenocarcinoma following endoscopic submucosal dissection.Siewert II型腺癌的临床病理特征：内镜黏膜下剥离术后贲门腺癌与Barrett食管腺癌的比较
Gastric Cancer. 2017 Jul;20(4):663-670. doi: 10.1007/s10120-016-0653-x. Epub 2016 Oct 25.
6
[Retrospective investigation of patients receiving additional surgery after endoscopic non-curative resection for early colorectal cancer].[早期结直肠癌内镜下非根治性切除术后接受额外手术患者的回顾性调查]
Zhonghua Wei Chang Wai Ke Za Zhi. 2020 May 25;23(5):486-491. doi: 10.3760/cma.j.cn.441530-20190612-00239.
7
Prevalence and prognostic significance of neuroendocrine cells in esophageal adenocarcinoma.食管腺癌中神经内分泌细胞的患病率及预后意义
Mod Pathol. 2000 May;13(5):475-81. doi: 10.1038/modpathol.3880081.
8
Endoscopic submucosal dissection for foregut neuroendocrine tumors: an initial study.内镜黏膜下剥离术治疗上消化道神经内分泌肿瘤：初步研究。
World J Gastroenterol. 2012 Oct 28;18(40):5799-806. doi: 10.3748/wjg.v18.i40.5799.
9
Neuroendocrine carcinoma of esophageal and gastric cardia: clinicopathologic and immunohistochemistry study of 80 cases.食管及贲门神经内分泌癌：80例临床病理及免疫组化研究
Oncotarget. 2017 Dec 22;9(12):10754-10764. doi: 10.18632/oncotarget.23610. eCollection 2018 Feb 13.
10
A neuroendocrine carcinoma with a well-differentiated adenocarcinoma component arising in Barrett's esophagus: a case report and literature review.一例起源于巴雷特食管的具有高分化腺癌成分的神经内分泌癌：病例报告及文献复习
Surg Case Rep. 2018 Aug 29;4(1):103. doi: 10.1186/s40792-018-0511-7.

本文引用的文献

1
Clinicopathological features and outcome of esophageal neuroendocrine tumor: A retrospective multicenter survey by the digestive endoscopy society of Taiwan.台湾消化内镜学会的一项回顾性多中心调查：食管神经内分泌肿瘤的临床病理特征和结局。
J Formos Med Assoc. 2021 Jan;120(1 Pt 2):508-514. doi: 10.1016/j.jfma.2020.06.024. Epub 2020 Jun 27.
2
The 2019 WHO classification of tumours of the digestive system.2019年世界卫生组织消化系统肿瘤分类。
Histopathology. 2020 Jan;76(2):182-188. doi: 10.1111/his.13975. Epub 2019 Nov 13.
3
Esophageal neuroendocrine tumor with initial presentation as painless forehead and neck masses: A case report.
Medicine (Baltimore). 2017 Dec;96(50):e9282. doi: 10.1097/MD.0000000000009282.
4
Neuroendocrine carcinoma of the esophagus: Clinicopathological and immunohistochemical features of 14 cases.食管神经内分泌癌：14例临床病理及免疫组化特征
PLoS One. 2017 Mar 13;12(3):e0173501. doi: 10.1371/journal.pone.0173501. eCollection 2017.
5
The clinical features and treatment modality of esophageal neuroendocrine tumors: a multicenter study in Korea.食管神经内分泌肿瘤的临床特征与治疗方式：韩国的一项多中心研究
BMC Cancer. 2014 Aug 7;14:569. doi: 10.1186/1471-2407-14-569.
6
Primary high-grade neuroendocrine carcinoma of the esophagus: a clinicopathologic and immunohistochemical study of 42 resection cases.食管原发性高级别神经内分泌癌：42 例切除标本的临床病理和免疫组织化学研究。
Am J Surg Pathol. 2013 Apr;37(4):467-83. doi: 10.1097/PAS.0b013e31826d2639.
7
Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study.305 例晚期胃肠神经内分泌癌（WHO G3）患者治疗和生存的预测和预后因素：北欧 NEC 研究。
Ann Oncol. 2013 Jan;24(1):152-60. doi: 10.1093/annonc/mds276. Epub 2012 Sep 11.
8
Metastasis of esophageal carcinoma to the brain.食管癌脑转移
Cancer. 2003 Nov 1;98(9):1925-33. doi: 10.1002/cncr.11737.