Zheng Jin-Hao, Xue Lu-Yu
Department of Critical Care Medicine, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China.
World J Clin Cases. 2022 Jun 26;10(18):6163-6167. doi: 10.12998/wjcc.v10.i18.6163.
Strongyloidiasis is usually a chronic infection but it can develop into a fatal disease in immunosuppressed patients.
A 68-year-old male with rheumatoid arthritis was treated with a variety of immunosuppressants for the past 3 years. Recently, the patient presented with a partial small-bowel obstruction, petechia, coughing and peripheral neuropathy. The diagnosis was difficult to clarify in other hospitals. Our hospital found larvae with active movement in the routine stool and sputum smears. The diagnosis of disseminated strongyloidiasis was established. Ivermectin combined with albendazole was used for treatment. The patient responded to therapy and was discharged.
This case underscores the importance of comprehensive differential diagnosis in immunocompromised patients.
类圆线虫病通常为慢性感染,但在免疫抑制患者中可发展为致命疾病。
一名68岁男性类风湿关节炎患者在过去3年中接受了多种免疫抑制剂治疗。最近,该患者出现部分小肠梗阻、瘀点、咳嗽和周围神经病变。在其他医院难以明确诊断。我院在常规粪便和痰液涂片检查中发现了活动的幼虫。确诊为播散性类圆线虫病。采用伊维菌素联合阿苯达唑进行治疗。患者治疗有效后出院。
该病例强调了免疫功能低下患者进行全面鉴别诊断的重要性。