Yu J J, Lu S C, Wu I H, Yu M C, Lee C N, Lin T P
Taiwan Provincial Chronic Disease Control Bureau, Taipei, R.O.C.
J Formos Med Assoc. 1995 Dec;94 Suppl 2:S162-5.
Strongyloides stercoralis is an intestinal nematode. In an immunocompetent host, Strongyloides infections usually produce only mild gastrointestinal symptoms. However, in an immunocompromised host, widespread dissemination of larvae to the extra-intestinal organs may occur. If unrecognized, the mortality rate is high. Here we report a case of disseminated strongyloidiasis in a chronic obstructive pulmonary disease (COPD) subject whose chest radiograph demonstrated multiple pneumonic patches and interstitial infiltrates. Strongyloides larvae were found in stool, sputum, and urine, and embryonated eggs were also found in sputum. The patient was treated successfully with mebendazole and alben albendazole. In conclusion, although high mortality rate is noted in disseminated strongyloidiasis, it is still a curable disease when early diagnosis and treatment could be made.
粪类圆线虫是一种肠道线虫。在免疫功能正常的宿主中，粪类圆线虫感染通常仅产生轻微的胃肠道症状。然而，在免疫功能低下的宿主中，幼虫可能会广泛播散至肠外器官。如果未被识别，死亡率很高。在此，我们报告一例慢性阻塞性肺疾病（COPD）患者发生播散性类圆线虫病的病例，其胸部X线片显示多个肺炎性斑片和间质浸润。在粪便、痰液和尿液中均发现了粪类圆线虫幼虫，痰液中还发现了感染期虫卵。患者接受甲苯咪唑和阿苯达唑治疗后成功治愈。总之，虽然播散性类圆线虫病死亡率较高，但早期诊断并治疗仍可治愈。
