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在四个选定非洲国家将对乙酰氨基酚不道德地用作食品嫩化剂:这是一个重大的公共卫生问题吗?

The Unethical Use of Paracetamol As a Food Tenderizer in Four Selected African Countries: A Major Public Health Concern?

作者信息

Afful Ewurabena Y, Frimpong-Manso Samuel, Bekoe Samuel O, Barfi Chris O, Opuni Kwabena F M, Oppong Mahmood B

机构信息

Department of Pharmaceutical Chemistry, School of Pharmacy, College of Health Sciences, University of Ghana, Legon, Ghana.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, PMB, Kumasi, Ghana.

出版信息

Drug Metab Bioanal Lett. 2022;15(3):159-165. doi: 10.2174/2949681015666220810125820.

Abstract

Paracetamol poisoning is the commonest cause of acute liver injury. Therefore, the unethical use of paracetamol as a food tenderizer poses a threat to human health. Although this is a common practice in Ghana, Uganda, Nigeria, and Kenya, there are few or no scientific records on the use of paracetamol as a food tenderizer and its deleterious effects, thus making it difficult to regulate this practice. This review aims to fully collate and present a systematic overview of the literature on the use of paracetamol as a food tenderizer in these countries, the potentially harmful effects posed by the practice, and measures in place to curb the situation. Additionally, this review aims to reveal the scientific gaps and areas requiring more research, thus providing a reference for further research to regulate this unscrupulous practice. From our extensive review of the literature, the high cost of fuel used in cooking and longer cooking times are the main reasons for the inappropriate use of paracetamol as a food tenderizer. Also, this review concludes that little has been done to create public awareness of this unethical practice. Furthermore, few ways to monitor, control and regulate this practice have been proposed.

摘要

对乙酰氨基酚中毒是急性肝损伤最常见的原因。因此,将对乙酰氨基酚不道德地用作食品嫩化剂对人类健康构成威胁。尽管在加纳、乌干达、尼日利亚和肯尼亚这是一种常见做法,但关于将对乙酰氨基酚用作食品嫩化剂及其有害影响的科学记录很少或根本没有,因此难以对这种做法进行监管。本综述旨在全面整理并系统概述关于在这些国家将对乙酰氨基酚用作食品嫩化剂的文献、这种做法可能造成的有害影响以及为遏制这种情况而采取的措施。此外,本综述旨在揭示科学空白和需要更多研究的领域,从而为进一步研究以规范这种不道德做法提供参考。通过对文献的广泛综述,烹饪中使用的燃料成本高以及烹饪时间长是不恰当地将对乙酰氨基酚用作食品嫩化剂的主要原因。此外,本综述得出结论,在提高公众对这种不道德做法的认识方面几乎没有采取什么措施。此外,几乎没有提出监测、控制和规范这种做法的方法。

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