Zuo W, Gao F, Yuan C W, Xiong S W, Li Z H, Zhang L, Yang K L, Li X F, Liu L, Wei L, Zhang P, Wang B, Gu Y M, Zhu H J, Zhao Z, Li X S
Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, China.
Department of Urology, Beijing Jiangong Hospital, Beijing 100054, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Aug 18;54(4):692-698. doi: 10.19723/j.issn.1671-167X.2022.04.018.
To study the trend of surgical type, surgical procedure and etiological distribution of upper urinary tract repair in recent 10 years.
The preoperative and perioperative variables and follow-up data of upper urinary tract reconstruction surgery in RECUTTER (Reconstruction of Urinary Tract: Technology, Epidemiology and Result) database from 2010 to 2021 were searched, collected and analyzed. The surgical type, surgical procedure, duration of hospitalization, time of operation, incidence of short-term complications, and proportion of the patients undergoing reoperations were compared between the two groups of 2010-2017 period and 2018-2021 period.
A total of 1 072 patients were included in the RECUTTER database. Congenital factors and iatrogenic injuries were the main causes of upper urinary tract repair. Among them, 129 (12.0%) patients had open operation, 403 (37.6%) patients had laparoscopic surgery, 322 (30.0%) patients had robot-assisted laparoscopic surgery and 218 (20.3%) patients had endourological procedure. In the last decade, the total number of surgeries showed a noticeable increasing annual trend and the proportion of robot-assisted laparoscopic surgery in 2018-2021 was significantly higher than that in 2010-2017 ( < 0.001). The 1 072 patients included 124 (11.6%) cases of ileal ureter replacements, 440 (41.1%) cases of pyeloplasty, 229 (21.4%) cases of balloon dilation, 109 (10.2%) cases of ureteral reimplantation, 49 (4.6%) cases of boari flap-Psoas hitch surgery, 60 (5.6%) cases of uretero-ureteral anastomosis, 61 (5.7%) cases of lingual mucosal onlay graft ureteroplasty or appendiceal onlay flap ureteroplasty. Pyeloplasty and balloon dilatation had been the main types of surgery, while the proportion of lingual mucosal onlay graft ureteroplasty plus appendiceal onlay flap ureteroplasty had increased significantly in recent years ( < 0.05). In addition, the time of operation was significantly increased ( < 0.05) after 2018, which was considered to be related to the sharp increase in the proportion of robot-assisted laparoscopic surgery. We found that minimally invasive surgery (endourological procedure and robot-assisted laparoscopic surgery) as an independent risk factor (=0.050, =0.472) could reduce the incidence of short-term post-operative complications.
We have justified the value of the RECUTTER database, created by the Institute of Urology, Peking University in data support for clinical research work, and provided valuable experience for the construction of other multi-center databases at home and abroad. In recent 10 years, we have observed that, in upper urinary tract reconstruction surgery, the surgery type tends to be minimally invasive and the surgery procedure tends to be complicated, suggesting the superiority of robot-assisted laparoscopic surgery.
研究近10年上尿路修复手术类型、手术方式及病因分布的变化趋势。
检索、收集并分析2010年至2021年RECUTTER(尿路重建:技术、流行病学与结果)数据库中上尿路重建手术的术前、围手术期变量及随访数据。比较2010 - 2017年和2018 - 2021年两组的手术类型、手术方式、住院时间、手术时间、短期并发症发生率及再次手术患者比例。
RECUTTER数据库共纳入1072例患者。先天性因素和医源性损伤是上尿路修复的主要原因。其中,129例(12.0%)患者接受开放手术,403例(37.6%)患者接受腹腔镜手术,322例(30.0%)患者接受机器人辅助腹腔镜手术,218例(20.3%)患者接受腔内泌尿外科手术。在过去十年中,手术总数呈明显的逐年上升趋势,2018 - 2021年机器人辅助腹腔镜手术的比例显著高于2010 - 2017年(<0.001)。1072例患者中,回肠代输尿管术124例(11.6%),肾盂成形术440例(41.1%),球囊扩张术229例(21.4%),输尿管再植术109例(10.2%),膀胱腰大肌悬吊术49例(4.6%),输尿管输尿管吻合术60例(5.6%),舌黏膜贴敷输尿管成形术或阑尾补片输尿管成形术61例(5.7%)。肾盂成形术和球囊扩张术一直是主要的手术类型,而近年来舌黏膜贴敷输尿管成形术加阑尾补片输尿管成形术的比例显著增加(<0.05)。此外,2018年后手术时间显著延长(<0.05),这被认为与机器人辅助腹腔镜手术比例的急剧增加有关。我们发现微创手术(腔内泌尿外科手术和机器人辅助腹腔镜手术)作为独立危险因素(=0.050,=0.472)可降低术后短期并发症的发生率。
我们证实了北京大学泌尿外科研究所创建的RECUTTER数据库在为临床研究工作提供数据支持方面的价值,并为国内外其他多中心数据库的建设提供了宝贵经验。近10年,我们观察到在上尿路重建手术中,手术类型趋于微创化,手术方式趋于复杂化,提示机器人辅助腹腔镜手术的优越性。