Silverman W A
Clin Perinatol. 1987 Jun;14(2):403-16.
Perinatal medicine is developing at an amazingly rapid pace. The brilliant record has been marred by recurrent tragedies following the general use of well-meaning, but poorly evaluated, therapeutic regimens for newborn infants and pregnant women. There is a clear and present need for increased public clamor demanding carefully designed, risk-limiting human experiments (randomized clinical trials) to provide interpretable evidence of benefit and risks of innovations before these are adopted as desirable medical and social policy.
围产期医学正以惊人的速度发展。然而，由于对新生儿和孕妇普遍采用了善意但评估不足的治疗方案，导致悲剧屡屡发生，这一辉煌成就因此蒙上了阴影。当前迫切需要公众发出更强烈的呼声，要求开展精心设计、风险可控的人体实验（随机临床试验），以便在将创新疗法作为理想的医疗和社会政策采用之前，提供关于其益处和风险的可解读证据。
