Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Department of Intensive Care Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland.
Curr Opin Crit Care. 2022 Dec 1;28(6):702-708. doi: 10.1097/MCC.0000000000000972. Epub 2022 Aug 10.
To summarize the recent evidence on acute mesenteric ischaemia (AMI).
The overall incidence of AMI is below 10/100 000 person years but increases exponentially with age. The overall mortality of AMI remains high, exceeding 50%, despite continuing progress and increasing availability of imaging and endovascular interventions. However, patients with (early) revascularization have significantly better outcomes. The majority of patients surviving the acute event are still alive at 1 year, but evidence on quality of life is scarce.Clinical suspicion of AMI is the key to timely diagnosis, with biphasic computed tomography-angiography the diagnostic method of choice. Currently, no biomarker has sufficient specificity to diagnose AMI.
Improved awareness and knowledge of AMI are needed to raise the suspicion of AMI in relevant patients and thereby to achieve better outcomes.
总结急性肠系膜缺血(AMI)的最新证据。
AMI 的总体发病率低于 10/100000 人年,但随着年龄的增长呈指数级增长。尽管影像学和血管内介入治疗不断进步且应用日益广泛,但 AMI 的总体死亡率仍然很高,超过 50%。然而,接受(早期)血运重建的患者预后显著改善。大多数在急性事件中幸存下来的患者在 1 年内仍然存活,但关于生活质量的证据很少。临床怀疑 AMI 是及时诊断的关键,双相 CT 血管造影是首选的诊断方法。目前,尚无生物标志物具有足够的特异性来诊断 AMI。
需要提高对 AMI 的认识和了解,以提高对相关患者 AMI 的怀疑,并由此获得更好的结果。