Gurel Abdullah, Baylan Burhan, Keles Ibrahim, Demirbas Arif, Karalar Mustafa, Eren Berkay, Ozen Ata, Oztekin Unal, Benlioglu Can, Dogan Ahmet Emin, Altan Mehmet, Ersekerci Erol, Cengiz Eren, Karadag Mert Ali, Müslümanoğlu Ahmet Yaser
Department of Urology, Afyon Health Sciences University Faculty of Medicine, Afyon, Turkey.
Department of Urology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey.
Turk J Urol. 2022 Sep;48(5):339-345. doi: 10.5152/tud.2022.22130.
The present study examines the effects of the coronavirus disease 2019 pandemic on radical prostatectomy performed as part of localized prostate cancer treatment in Turkey.
A retrospective analysis was made of the data of 176 patients from 8 centers in Turkey who underwent radical prostatectomy due to localized prostate cancer over the 2 years spanning March 1, 2019, to February 28, 2021. Within this timeframe, March 1, 2019, to February 28, 2020, was denoted the 1-year pre-coronavirus disease 2019 period, while March 1, 2020, to February 28, 2021, was denoted the 1-year coronavirus disease 2019 period. An analysis was made of whether there was a difference in the number of radical prostatectomies performed for prostate cancer, the time from biopsy to operation, and the biopsy and radical prostatectomy pathology between the 2 periods.
It was found that the number of radical prostatectomies performed for localized prostate cancer during the coronavirus disease 2019 pandemic was statistically and highly significantly fewer than in the pre-coronavirus disease 2019 period (P <.001). The patients diagnosed with Gleason 3+3 (low risk) prostate cancer were statistically significantly fewer in number in the coronavirus disease 2019 period (P <.001). The pathological Gleason score was upgrading than the biopsy Gleason score in all patients who underwent in both periods (P <.001). When the periods were compared, the pathological involvement determined by lymph node dissection performed during radical prostatectomy was found to be decreased in the coronavirus disease 2019 period, although the difference was not statistically significant (P =.051).
As with many diseases, the diagnosis and treatment of prostate cancer have been adversely affected by the coronavirus disease 2019 pandemic.
本研究探讨2019年冠状病毒病大流行对土耳其作为局限性前列腺癌治疗一部分的根治性前列腺切除术的影响。
对2019年3月1日至2021年2月28日这两年间土耳其8个中心因局限性前列腺癌接受根治性前列腺切除术的176例患者的数据进行回顾性分析。在此时间范围内，2019年3月1日至2020年2月28日被定义为2019年冠状病毒病前1年时期，而2020年3月1日至2021年2月日被定义为2019年冠状病毒病1年时期。分析了这两个时期前列腺癌根治性前列腺切除术的数量、活检至手术的时间以及活检和根治性前列腺切除术病理是否存在差异。
发现在2019年冠状病毒病大流行期间，因局限性前列腺癌进行的根治性前列腺切除术的数量在统计学上显著少于2019年冠状病毒病前时期（P <.001）。在2019年冠状病毒病时期，诊断为Gleason 3+3（低风险）前列腺癌的患者数量在统计学上显著减少（P <.001）。在两个时期接受手术的所有患者中，病理Gleason评分均高于活检Gleason评分（P <.001）。当比较这两个时期时，发现2019年冠状病毒病时期根治性前列腺切除术期间进行的淋巴结清扫所确定的病理累及有所减少，尽管差异无统计学意义（P =.051）。
与许多疾病一样，2019年冠状病毒病大流行对前列腺癌的诊断和治疗产生了不利影响。
