从小鼠血清中分离出的α1-酸性糖蛋白的部分特性鉴定
Partial characterization of alpha 1-acid glycoprotein isolated from mouse serum.
作者信息
McGregor R W, Weselake R J, Peltz B A, Aoki F Y, Friesen A D
出版信息
Comp Biochem Physiol B. 1987;86(3):493-9. doi: 10.1016/0305-0491(87)90437-8.
PMID:3595087
Abstract
AGP was purified from mouse serum by perchloric acid treatment and CM-Sepharose chromatography. Induction of inflammation with turpentine resulted in a 10-fold increase in the serum level of mouse AGP, indicating mouse AGP is an acute phase reactant. Biochemical characterization of mouse AGP indicated similarity with human and rat AGP.
摘要
通过高氯酸处理和CM-琼脂糖凝胶柱层析从鼠血清中纯化出抗胰蛋白酶（AGP）。用松节油诱导炎症会导致小鼠AGP血清水平增加10倍，这表明小鼠AGP是一种急性期反应物。小鼠AGP的生化特性表明它与人和大鼠的AGP相似。
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