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2
Periumbilical neuropathic pruritus in an infant: presentation of a spinal intramedullary neoplasm.婴儿脐周神经性瘙痒:脊髓髓内肿瘤的表现
J Eur Acad Dermatol Venereol. 2022 Feb;36(2):e132-e133. doi: 10.1111/jdv.17696. Epub 2021 Oct 2.
3
Cannabinoids for the treatment of refractory neuropathic pruritus in amyotrophic lateral sclerosis: A case report.大麻素治疗肌萎缩侧索硬化症难治性神经性瘙痒:病例报告。
Palliat Med. 2022 Jan;36(1):208-211. doi: 10.1177/02692163211045314. Epub 2021 Sep 11.
4
Botulinum toxin type A therapy for bilateral focal neuropathic pruritus in multiple sclerosis: a case report.A型肉毒毒素治疗多发性硬化症双侧局灶性神经病理性瘙痒:病例报告。
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5
A protracted, postherpetic neuralgic ulcer treated with risperidone and intranasal butorphanol.一例用利培酮和鼻内布托啡诺治疗的迁延性带状疱疹后神经痛溃疡
JAAD Case Rep. 2021 Jul 13;15:7-10. doi: 10.1016/j.jdcr.2021.06.026. eCollection 2021 Sep.
6
Gabapentinoids for Pruritus in Older Adults: A Narrative Review.加巴喷丁类药物用于老年人瘙痒症:一项叙述性综述
Dermatol Ther (Heidelb). 2021 Jun;11(3):669-679. doi: 10.1007/s13555-021-00513-z. Epub 2021 Mar 15.
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Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition.中枢阿片受体通过去抑制介导吗啡诱导的瘙痒和慢性瘙痒。
Brain. 2021 Mar 3;144(2):665-681. doi: 10.1093/brain/awaa430.
8
Intranasal butorphanol rescue therapy for the treatment of intractable pruritus: A case series from the Johns Hopkins Itch Clinic.鼻内注射布托啡诺挽救疗法治疗顽固性瘙痒:约翰霍普金斯瘙痒诊所的病例系列
J Am Acad Dermatol. 2020 Nov;83(5):1529-1533. doi: 10.1016/j.jaad.2020.07.017. Epub 2020 Jul 15.
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Doxepin cream is not effective in reducing itch in burn scar patients: A multicenter triple-blind randomized clinical crossover trial.多塞平乳膏治疗烧伤后瘢痕所致瘙痒无效:一项多中心、三盲、随机交叉临床试验。
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[神经性瘙痒——基于证据的治疗建议]

[Neuropathic pruritus-Evidence-based treatment recommendations].

作者信息

Baka Panoraia, Birklein Frank

机构信息

Klinik für Neurologie, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

出版信息

Nervenarzt. 2023 Feb;94(2):136-141. doi: 10.1007/s00115-022-01369-0. Epub 2022 Aug 11.

DOI:10.1007/s00115-022-01369-0
PMID:35951052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9898430/
Abstract

Neuropathic pruritus is a previously neglected symptom of a wide range of neurological diseases. Peripheral nerve or root compression syndromes, space-occupying lesions of the central nervous system, chronic inflammatory neurological diseases and polyneuropathy can cause neuropathic pruritus. Even when the identification of the underlying neurological disease is successful, a direct causal treatment is not always possible, hence an effective symptomatic treatment remains the only therapeutic option. The purpose of this review article is to present the current literature on various therapeutic agents and options in the treatment of neuropathic pruritus.

摘要

神经性瘙痒是多种神经系统疾病中一种先前被忽视的症状。周围神经或神经根压迫综合征、中枢神经系统占位性病变、慢性炎症性神经系统疾病和多发性神经病均可引起神经性瘙痒。即使成功识别出潜在的神经系统疾病,也并非总能进行直接的病因治疗,因此有效的对症治疗仍然是唯一的治疗选择。这篇综述文章的目的是介绍目前有关治疗神经性瘙痒的各种治疗药物和选择的文献。