State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
Environ Sci Pollut Res Int. 2022 Oct;29(46):69197-69212. doi: 10.1007/s11356-022-22451-9. Epub 2022 Aug 11.
Metal toxicity can largely affect the growth and yield of numerous plant species. Plants have developed specific mechanisms to withstand the varying amounts of metals. One approach involves utilization of microRNAs (miRNAs) that are known for cleaving transcripts or inhibiting translation to mediate post-transcriptional control. Use of transcription factors (TFs) or gene regulation in metal detoxification largely depends on metal-responsive miRNAs. Moreover, systemic signals and physiological processes for plants response to metal toxicities are likewise controlled by miRNAs. Therefore, it is necessary to understand miRNAs and their regulatory networks in relation to metal stress. The miRNA-based approach can be important to produce metal-tolerant plant species. Here, we have reviewed the importance of plant miRNAs and their role in mitigating metal toxicities. The current review also discusses the specific advances that have occurred as a result of the identification and validation of several metal stress-responsive miRNAs.
金属毒性会极大地影响许多植物物种的生长和产量。植物已经发展出特定的机制来抵御不同数量的金属。一种方法涉及利用 microRNAs (miRNAs)，已知它们可以切割转录物或抑制翻译来介导转录后控制。在金属解毒中使用转录因子 (TFs) 或基因调控在很大程度上取决于金属响应的 miRNAs。此外，植物对金属毒性的反应的系统信号和生理过程也受到 miRNAs 的控制。因此，有必要了解与金属胁迫有关的 miRNAs 及其调控网络。基于 miRNA 的方法对于生产耐金属植物物种可能很重要。在这里，我们回顾了植物 miRNAs 的重要性及其在减轻金属毒性方面的作用。本综述还讨论了由于鉴定和验证几种金属胁迫响应 miRNAs 而取得的具体进展。
