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瑞士普通实践中慢性肾病治疗的质量和差异:一项回顾性数据库研究。

Quality and variation of care for chronic kidney disease in Swiss general practice: A retrospective database study.

机构信息

Institute of Primary Care, University of Zurich and University Hospital Zurich, Zurich, Switzerland.

出版信息

PLoS One. 2022 Aug 11;17(8):e0272662. doi: 10.1371/journal.pone.0272662. eCollection 2022.

Abstract

BACKGROUND

Chronic kidney disease (CKD) is a common condition in general practice. Data about quality and physician-level variation of CKD care provided by general practitioners is scarce. In this study, we evaluated determinants and variation of achievement of 14 quality indicators for CKD care using electronic medical records data from Swiss general practice during 2013-2019.

METHODS

We defined two patient cohorts from 483 general practitioners, one to address renal function assessment in patients with predisposing conditions (n = 47,201, median age 68 years, 48.7% female) and one to address care of patients with laboratory-confirmed CKD (n = 14,654, median age 80 years, 57.5% female). We investigated quality indicator achievement with mixed-effect logistic regression and expressed physician-level variation as intraclass correlation coefficients (ICCs) and range odds ratios (rORs).

RESULTS

We observed the highest quality indicator achievement rate for withholding non-steroidal anti-inflammatory drug prescription in patients with CKD staged G2-3b within 12 months of follow-up (82.6%), the lowest for albuminuria assessment within 18 months of follow-up (18.1%). Highest physician-level variation was found for renal function assessment during 18 months of follow-up in patients with predisposing conditions (diabetes: ICC 0.31, rOR 26.5; cardiovascular disease: ICC 0.28, rOR 17.4; hypertension: ICC 0.24, rOR 17.2).

CONCLUSION

This study suggests potentially unwarranted variation in general practice concerning RF assessment in patients affected by conditions predisposing for CKD. We further identified potential gaps in quality of CKD monitoring as well as lower quality of CKD care for female patients and patients not affected by comorbidities.

摘要

背景

慢性肾脏病(CKD)是普通科常见的病症。关于普通科医生提供的 CKD 护理的质量和医生层面的差异的数据很少。在这项研究中,我们使用了来自 2013 年至 2019 年瑞士普通科的电子病历数据,评估了 14 项 CKD 护理质量指标的实现情况及其决定因素和医生层面的差异。

方法

我们从 483 名普通科医生中定义了两个患者队列,一个队列用于评估有潜在疾病的患者的肾功能评估(n=47201,中位年龄 68 岁,48.7%为女性),另一个队列用于评估有实验室确诊的 CKD 的患者的护理(n=14654,中位年龄 80 岁,57.5%为女性)。我们使用混合效应逻辑回归调查了质量指标的实现情况,并使用组内相关系数(ICC)和范围比值比(rOR)表示医生层面的差异。

结果

我们观察到在随访 12 个月内,对处于 G2-3b 期的 CKD 患者进行非甾体抗炎药处方的抑制率最高(82.6%),在随访 18 个月内进行白蛋白尿评估的比率最低(18.1%)。在有潜在疾病的患者中,随访 18 个月时的肾功能评估医生层面的差异最大(糖尿病:ICC 0.31,rOR 26.5;心血管疾病:ICC 0.28,rOR 17.4;高血压:ICC 0.24,rOR 17.2)。

结论

这项研究表明,普通科医生在评估有 CKD 潜在疾病的患者的 RF 方面可能存在不必要的差异。我们进一步发现,在 CKD 监测方面存在潜在的质量差距,以及女性患者和无合并症患者的 CKD 护理质量较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ab2/9371276/7969269dee79/pone.0272662.g001.jpg

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