Patel Ankit, Kane John M
Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263, USA.
Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14263, USA.
Surg Clin North Am. 2022 Aug;102(4):551-565. doi: 10.1016/j.suc.2022.05.002. Epub 2022 Jun 24.
The potentially curative treatment of sarcoma is negative margin wide resection, the clinical tumor with an en bloc margin of surrounding tissue potentially contains microscopic tumor. Planned margins should be 1 to 2 cm but can be less for oncologically equivalent barrier tissues or to preserve an adjacent critical structure. Tumor spillage should be avoided. The role of radiation and/or chemotherapy should be discussed before surgery, as there are potential benefits to preoperative administration. An isolated local recurrence is potentially curable. Amputation is rarely necessary and should only be pursued after other limb salvage treatment options have been considered.
肉瘤的潜在治愈性治疗方法是进行切缘阴性的广泛切除，临床肿瘤连同周围组织的整块切缘可能含有微小肿瘤。计划切缘应为1至2厘米，但对于肿瘤学等效的屏障组织或为保留相邻关键结构，切缘可更小。应避免肿瘤溢出。手术前应讨论放疗和/或化疗的作用，因为术前给予有潜在益处。孤立的局部复发有可能治愈。很少需要截肢，只有在考虑了其他保肢治疗方案后才应进行。
