Department of Paediatrics I, University Hospital, University of Duisburg-Essen, 45147 Essen, Germany.
Centre for Translational Neuro- and Behavioural Sciences (C-TNBS), Faculty of Medicine, University of Duisburg-Essen, 45147 Essen, Germany.
Int J Environ Res Public Health. 2022 Aug 3;19(15):9524. doi: 10.3390/ijerph19159524.
Evidence that music therapy stabilises vital parameters in preterm infants is growing, but the optimal setting for therapy is still under investigation. Our study aimed to quantify the effect of physical contact during live music therapy in preterm infants born < 32 weeks’ gestational age (GA) on post-therapy vital sign values. Live music therapy was delivered twice-weekly until discharge from hospital to 40 stable infants < 32 weeks’ GA. Baseline and post-therapy heart rate, respiratory rate, oxygen saturation and physical contact during each session were recorded. 159 sessions were performed with, and 444 sessions without, physical contact. Descriptive and multivariable regression analyses based on directed acyclic graphs were performed. The mean GA was 28.6 ± 2.6 weeks, and 26 (65%) infants were male. Mean absolute values for heart and respiratory rates lowered during music therapy regardless of physical contact. The mean post-therapy SaO2 was higher compared to baseline values regardless of physical contact (mean differences −8.6 beats/min; −13.3 breaths/min and +2.0%). There were no clinically relevant changes in vital sign responses between therapy sessions, with or without physical contact, or adjusted post-therapy values for any of the studied vital signs. Physical contact caused better baseline and post-therapy vital sign values but did not enhance the vital sign response to music therapy. Thus, the effect of music therapy on preterm infants’ vital signs is independent of physical contact and parents’ presence during music therapy in the neonatal intensive care unit.
有证据表明，音乐疗法可以稳定早产儿的生命体征参数，但最佳的治疗环境仍在研究之中。我们的研究旨在量化在胎龄<32 周的早产儿中进行的现场音乐治疗期间的身体接触对治疗后生命体征值的影响。现场音乐治疗每周进行两次，直到这些早产儿出院，达到 40 周稳定状态。记录了每次治疗前后的心率、呼吸频率、血氧饱和度和身体接触情况。有 159 次治疗有身体接触，444 次治疗没有身体接触。基于有向无环图的描述性和多变量回归分析。平均胎龄为 28.6±2.6 周，26 名（65%）婴儿为男性。无论是否有身体接触，音乐治疗期间的心率和呼吸率绝对值均降低。无论是否有身体接触，治疗后的 SaO2 平均值均高于基线值（平均差异-8.6 次/分；-13.3 次/分和+2.0%）。在有或没有身体接触的情况下，或调整治疗后的任何生命体征值后，治疗期间的生命体征反应之间没有临床相关的变化。身体接触可改善治疗前后的生命体征值，但不会增强音乐疗法对早产儿生命体征的反应。因此，音乐疗法对早产儿生命体征的影响独立于身体接触和父母在新生儿重症监护病房进行音乐治疗时的存在。
