Dudzicz-Gojowy Sylwia, Więcek Andrzej, Adamczak Marcin
Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Francuska 20-24, 40-027 Katowice, Poland.
J Clin Med. 2022 Jul 27;11(15):4365. doi: 10.3390/jcm11154365.
infection (CDI) is one of the most common causes of antibiotic-associated diarrhea. The pathogenesis of this infection participates in the unstable colonization of the intestines with the physiological microbiota. Solid-organ-transplant (SOT) patients and patients after hematopoietic stem cell transplantation are more prone to CDI compared to the general population. The main CDI risk factors in these patients are immunosuppressive therapy and frequent antibiotic use leading to dysbiosis. The current review article provides information about the risk factors, incidence and course of CDI in patients after liver, kidney, heart and lung transplantation and hematopoietic stem cell transplantation.
艰难梭菌感染（CDI）是抗生素相关性腹泻最常见的病因之一。这种感染的发病机制涉及肠道内生理微生物群的不稳定定植。与普通人群相比，实体器官移植（SOT）患者和造血干细胞移植后的患者更容易发生CDI。这些患者发生CDI的主要危险因素是免疫抑制治疗和频繁使用抗生素导致的生态失调。本综述文章提供了有关肝、肾、心、肺移植及造血干细胞移植后患者发生CDI的危险因素、发病率和病程的信息。
