Hackney Diabetes Centre, Homerton Healthcare NHS Foundation Trust, London E9 6SR, UK.
Endocrinology Department, Barts Health NHS Trust, London E1 1BB, UK.
Nutrients. 2022 Jul 30;14(15):3146. doi: 10.3390/nu14153146.
(1) Background: Formula low energy diets (LED) are effective at inducing weight loss and type 2 diabetes (T2DM) remission. However, the effect of LED programmes in ethnic minority groups in the UK is unknown. (2) Methods: A service-evaluation was undertaken of a group-based LED, total diet replacement (TDR) programme in London, UK. The programme included: a 12-week TDR phase, 9-week food reintroduction and a 31-week weight maintenance phase and was delivered by a diabetes multi-disciplinary team. (3) Results: Between November 2018 and March 2020, 216 individuals were referred, 37 commenced the programme, with 29 completing (78%). The majority were of Black British (20%) ethnicity with a mean (SD) age of 50.4 (10.5) years, a body mass index of 34.4 (4.4) kg/m and a T2DM duration of 4.2 (3.6) years. At 12 months, 65.7% achieved T2DM remission, with a mean bodyweight loss of 11.6 (8.9) kg. Completers lost 15.8 (5.3) kg, with 31.4% of participants achieving ≥15 kg weight loss. Quality of life measures showed significant improvements. (4) Conclusions: This service evaluation shows for the first time in the UK that a group-based formula LED programme can be effective in achieving T2DM remission and weight loss in an ethnical diverse population.
(1)背景:配方低能量饮食(LED)在诱导体重减轻和 2 型糖尿病(T2DM)缓解方面非常有效。然而,英国少数民族群体中 LED 方案的效果尚不清楚。(2)方法:对英国伦敦的一种基于小组的 LED(全饮食替代 TDR)方案进行了服务评估。该方案包括:12 周的 TDR 阶段、9 周的食物重新引入和 31 周的体重维持阶段,由糖尿病多学科团队提供。(3)结果:2018 年 11 月至 2020 年 3 月期间,有 216 人被转介,37 人开始参加该方案,其中 29 人完成(78%)。大多数人是英国黑人(20%),平均年龄(标准差)为 50.4(10.5)岁,体重指数为 34.4(4.4)kg/m,T2DM 持续时间为 4.2(3.6)年。在 12 个月时,65.7%的人达到 T2DM 缓解,平均体重减轻 11.6(8.9)kg。完成者体重减轻 15.8(5.3)kg,其中 31.4%的参与者体重减轻≥15kg。生活质量指标显示出显著改善。(4)结论:这项服务评估首次表明,基于小组的配方 LED 方案在一个种族多样化的人群中可以有效地实现 T2DM 缓解和体重减轻。