Bömelburg T, Lenz W, Eusterbrock T
Eur J Pediatr. 1987 May;146(3):301-2. doi: 10.1007/BF00716480.
A premature female infant had the characteristic features of the median cleft face syndrome in association with holoprosencephaly, agenesis of the corpus callosum, hydrocephalus and choanal atresia. Whereas the nervous system is rarely affected in patients with the median cleft face syndrome, severe mental retardation has been reported in three previously published cases and is suggested in our own patient. All had an associated agenesis of the corpus callosum.
一名早产女婴具有正中面裂综合征的特征性表现，同时伴有前脑无裂畸形、胼胝体发育不全、脑积水和后鼻孔闭锁。正中面裂综合征患者的神经系统很少受累，但在之前发表的3例病例中报告了严重智力发育迟缓，我们的患者也有此迹象。所有病例均伴有胼胝体发育不全。
