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早产是全身麻醉下早期腹股沟疝修补术后呼吸衰竭的关键风险因素。

Prematurity is a critical risk factor for respiratory failure after early inguinal hernia repair under general anesthesia.

作者信息

Schroepf Sebastian, Mayle Paulina M, Kurz Matthias, Wermelt Julius Z, Hubertus Jochen

机构信息

Department of Pediatrics and Neonatology, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.

Department of Internal Medicine, University Hospital Augsburg, Augsburg, Germany.

出版信息

Front Pediatr. 2022 Jul 25;10:843900. doi: 10.3389/fped.2022.843900. eCollection 2022.

Abstract

INTRODUCTION

The purpose of this study was to determine the earliest timing of inguinal hernia repair under general anesthesia with minimized risk for respiratory complications during postoperative course.

METHODS

We performed a monocentric analysis of patient records of premature and full-term infants undergoing inguinal hernia repair between 2009 and 2016. In addition to demographic and medical parameters, preexisting conditions and the perioperative course were recorded.

RESULTS

The study included 499 infants (preterm = 285; full term = 214). The number of subsequently ventilated patients was particularly high among preterm infants with bronchopulmonary dysplasia, up to 45.3% ( < 0.001). Less than 10% of subsequent ventilation occurred in preterm infants after 45 weeks of postmenstrual age at the time of surgery or in patients with a body weight of more than 4,100 g. Preterm infants with a bronchopulmonary dysplasia had an increased risk of apneas ( < 0.05). Only 10% of the preterm babies with postoperative apneas weighed more than 3,600 g at the time of surgery or were older than 44 weeks of postmenstrual age.

CONCLUSION

Our data indicate that after the 45th week of postmenstrual age and a weight above 4,100 g, the risk for respiratory failure after general anesthesia seems to be significantly decreased in preterm infants.

摘要

引言

本研究的目的是确定在全身麻醉下进行腹股沟疝修补术的最早时机,以使术后呼吸并发症的风险降至最低。

方法

我们对2009年至2016年间接受腹股沟疝修补术的早产儿和足月儿的病历进行了单中心分析。除了人口统计学和医学参数外,还记录了既往疾病和围手术期过程。

结果

该研究纳入了499名婴儿(早产儿=285名;足月儿=214名)。在患有支气管肺发育不良的早产儿中,随后需要通气的患者数量特别高,高达45.3%(<0.001)。在手术时月经龄45周后的早产儿或体重超过4100g的患者中,随后需要通气的比例不到10%。患有支气管肺发育不良的早产儿呼吸暂停风险增加(<0.05)。术后出现呼吸暂停的早产儿中,只有10%在手术时体重超过3600g或月经龄超过44周。

结论

我们的数据表明,月经龄45周后且体重超过4100g,早产儿全身麻醉后呼吸衰竭的风险似乎显著降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/9357901/f40e2e7212c4/fped-10-843900-g001.jpg

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