Hu Min, Zhang Xin, Hu Can, Teng Teng, Tang Qi-Zhu
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, China.
Front Cardiovasc Med. 2022 Jul 26;9:939757. doi: 10.3389/fcvm.2022.939757. eCollection 2022.
Isthmin-1 is a secreted protein with multiple capability; however, it truly attracts our attention since the definition as an adipokine in 2021, which exerts indispensable roles in various pathophysiological processes through the endocrine or autocrine manners. In this review, we summarize recent knowledge of isthmin-1, including its distribution, structure, receptor and potential function.
肌动蛋白-1是一种具有多种功能的分泌蛋白;然而,自2021年被定义为脂肪因子以来,它真正引起了我们的关注,该蛋白通过内分泌或自分泌方式在各种病理生理过程中发挥着不可或缺的作用。在这篇综述中,我们总结了关于肌动蛋白-1的最新知识,包括其分布、结构、受体和潜在功能。