Ou Mengdang, Guo Xiaozhen, Li Ying, Zhang Haili, Liu Ting, Liu Qun, Wei Wen, Luo Xiaoqing, Zhang Yanyan
Department of Infectious Diseases, The Fifth Hospital of Sun Yat-sen University Zhuhai 519000, Guangdong, China.
Am J Transl Res. 2022 Jul 15;14(7):5187-5194. eCollection 2022.
To explore the difference in anxiety and mental health of patients with liver cirrhosis with different compensatory abilities, so as to provide comprehensive treatment measures such as individualized psychological support for patients.
In this retrospective study, a total of 175 patients with liver cirrhosis admitted to the Department of Infectious Diseases, Fifth Hospital of Sun Yat-sen University from January to December 2019 were included and divided into a compensated group (n=77) and a decompensated group (n=98). The anxiety of patients was evaluated on the day of admission, one week after hospitalization, and the day of discharge using the Self-Rating Anxiety Scale (SAS). Psychological investigations were conducted on the two groups of patients with cirrhosis.
The SAS score of patients in the decompensated group was higher than that of the compensated group on the day of admission (48.62±6.35 vs. 37.68±8.94, F=20.313), one week after hospitalization (56.95±7.47 vs. 42.79±10.77, F=29.879), and on the day of discharge (42.95±7.85 vs. 36.43±9.29, F=7.110) (P<0.05). The SAS score of male patients in the decompensated group was higher than that of the compensated group on the day of admission (47.50±6.25 vs. 36.70±9.92, t=-4.112), one week after hospitalization (57.25±5.80 vs. 42.10±13.24, t=-4.538) and on the day of discharge (42.33±7.34 vs. 36.19±9.65, t=-2.162) (all P<0.05). The SAS score of 40-59 year-old patients of the decompensated group was higher than that of patients in the compensated group of the same age on the day of admission (51.80±6.26 vs. 36.84±8.57, t=-4.372), one week after hospitalization (60.6±7.06 vs. 42.94±10.33, t=-4.382), and on the day of discharge (48.60±4.16 vs. 37.32±10.23, t=-3.768) (P<0.05). The SAS score of female patients in the decompensated group was higher than that in the compensated group at one week after hospitalization (56.56±9.65 vs. 35.45±18.66, t=-4.617) (P<0.05). There was no difference in the SAS score between patients of different groups on the day of admission and the day of discharge (P>0.05).
The anxiety of patients with different compensatory abilities of the liver is adversely affected by the severity of their illness and the length of hospitalization. The anxiety of male patients in the decompensated group is more significant than that of patients in the compensated group, while no significant difference was observed in anxiety between female patients in the decompensated group and those in the compensated group on the day of admission and discharge. It is necessary to strengthen psychological intervention, optimize the treatment methods, and reduce the average hospital stay in decompensated patients.
探讨不同代偿能力肝硬化患者焦虑及心理健康状况的差异，为患者提供个体化心理支持等综合治疗措施。
本回顾性研究纳入2019年1月至12月中山大学附属第五医院感染科收治的175例肝硬化患者，分为代偿组（n = 77）和失代偿组（n = 98）。分别于入院当日、住院1周后及出院当日采用焦虑自评量表（SAS）评估患者焦虑状况。对两组肝硬化患者进行心理调查。
失代偿组患者入院当日（48.62±6.35 vs. 37.68±8.94，F = 20.313）、住院1周后（56.95±7.47 vs. 42.79±10.77，F = 29.879）及出院当日（42.95±7.85 vs. 36.43±9.29，F = 7.110）的SAS评分均高于代偿组（P<0.05）。失代偿组男性患者入院当日（47.50±6.25 vs. 36.70±9.92，t = -4.112）、住院1周后（57.25±5.80 vs. 42.10±13.24，t = -4.538）及出院当日（42.33±7.34 vs. 36.19±9.65，t = -2.162）的SAS评分均高于代偿组（均P<0.05）。失代偿组40 - 59岁患者入院当日（51.80±6.26 vs. 36.84±8.57，t = -4.372）、住院1周后（60.6±7.06 vs. 42.94±10.33，t = -4.382）及出院当日（48.60±4.16 vs. 37.32±10.23，t = -3.768）的SAS评分均高于同年龄段代偿组患者（P<0.05）。失代偿组女性患者住院1周后的SAS评分高于代偿组（56.56±9.65 vs. 35.45±18.66，t = -4.617）（P<0.05）。不同组患者入院当日及出院当日的SAS评分差异无统计学意义（P>0.05）。
肝脏不同代偿能力患者的焦虑受病情严重程度及住院时间的不良影响。失代偿组男性患者焦虑较代偿组患者更显著，而失代偿组女性患者与代偿组女性患者入院及出院当日焦虑无明显差异。有必要加强心理干预，优化治疗方法，缩短失代偿患者平均住院时间。
