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不同牙种植体引导骨再生中牙科修复膜的临床疗效和安全性的Meta 分析。

Clinical Efficacy and Safety of Different Dental Prosthetic Membranes in Guided Bone Regeneration during Dental Implants: A Meta-Analysis.

机构信息

Department of Stomatology, The 940th Hospital of Joint Logistic Support Force of PLA, Lanzhou 730050, China.

Endocrinology Department, The 940th Hospital of Joint Logistic Support Force of PLA, Lanzhou 730050, China.

出版信息

Comput Intell Neurosci. 2022 Jul 31;2022:3245014. doi: 10.1155/2022/3245014. eCollection 2022.

Abstract

. To evaluate clinical efficacy and safety of absorbable and non-absorbable dental restorative membranes in guided bone regeneration (GBR). Articles concerning absorbable and non-absorbable prosthetic membrane-related studies of GBR were screened from multiple databases. In the end, 526 postoperative patients who met eligibility criteria were screened for the study from eight trials. The results showed that the repair success rate of the experimental group (absorbable dental restorative membrane) was higher than that of the control group (non-absorbable dental restorative membrane) (RR = 1.18, 95% CI [1.11,1.26], and the total physical therapy effect was  < 0.0001,  = 0%), and the height of bone graft in the experimental group was higher than that in the control group (MD = 0.67, 95% CI [0.11, 1.23]). The thickness of bone graft in the experimental group was higher than that in the control group (MD = 0.43, 95% CI [0.30,0.56],  < 0.00001,  = 61%), and the adverse events in the experimental group were less than those in the control group (RR = 0.31, 95% CI [0.18, 0.51],  < 0.00001,  = 13%). Absorbable prosthetic membrane is superior to non-absorbable prosthetic membrane in clinical efficacy and safety.

摘要

. 评价可吸收和不可吸收牙科修复膜在引导骨再生(GBR)中的临床疗效和安全性。从多个数据库筛选出关于可吸收和不可吸收修复膜的 GBR 相关研究的文章。最终,从 8 项试验中筛选出符合纳入标准的 526 例术后患者进行本研究。结果显示,实验组(可吸收牙科修复膜)的修复成功率高于对照组(不可吸收牙科修复膜)(RR=1.18,95%CI[1.11,1.26],总物理治疗效果 < 0.0001,  = 0%),实验组的植骨高度高于对照组(MD=0.67,95%CI[0.11,1.23])。实验组的植骨厚度高于对照组(MD=0.43,95%CI[0.30,0.56], < 0.00001,  = 61%),实验组的不良事件少于对照组(RR=0.31,95%CI[0.18,0.51], < 0.00001,  = 13%)。可吸收修复膜在临床疗效和安全性方面优于不可吸收修复膜。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bd3/9357784/755fb2209613/CIN2022-3245014.004.jpg

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