Yuyao City Third People's Hospital, Yuyao City, Zhejiang 315400, China.
Mediators Inflamm. 2022 Aug 2;2022:5741114. doi: 10.1155/2022/5741114. eCollection 2022.
In order to further explore the therapeutic effects of high-frequency and low-frequency repetitive transcranial magnetic stimulation on depression and cognitive function in the elderly, this paper proposed a study on cortical plasticity mechanism and efficacy prediction of repetitive transcranial magnetic stimulation based on continuous short pulse fast pulse stimulation (CTBS). This paper selected 92 patients with depression in a hospital from January to December 2020 as the research object and divided them into control group, low-frequency group, and high-frequency group, 31 cases, 29 cases, and 32 cases, respectively. The continuous short pulse rapid pulse stimulation (CTBS) mode was used to explore the effect of brain network on patients' emotional processing. After clinical treatment contrast, there was no significant difference in HAMD-24 scores and RBANS scores before treatment ( > 0.05), and there was a significant negative correlation between factors of cognitive impairment in patients and RBANS scores ( < 0.01 or < 0.05), so it was proved that the repeated transcranial magnetic stimulation (cTBS) could be used as an effective treatment for depression.
为进一步探讨高频和低频重复经颅磁刺激对老年抑郁症及认知功能的治疗作用，本文提出一种基于连续短脉冲快速脉冲刺激（CTBS）的重复经颅磁刺激皮质可塑性机制及疗效预测研究。本研究选取 2020 年 1 月至 12 月在某医院就诊的 92 例抑郁症患者为研究对象，将其分为对照组、低频组和高频组，每组 31 例、29 例和 32 例。采用连续短脉冲快速脉冲刺激（CTBS）模式，探讨脑网络对患者情绪处理的影响。经过临床治疗对比，治疗前 HAMD-24 评分和 RBANS 评分差异无统计学意义（>0.05），患者认知障碍各因子与 RBANS 评分呈显著负相关（<0.01 或<0.05），说明重复经颅磁刺激（cTBS）可作为治疗抑郁症的有效手段。
