Kalinichenko Liubov S, Kornhuber Johannes, Müller Christian P
Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany.
Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Transl Neurosci. 2022 Jul 26;13(1):198-200. doi: 10.1515/tnsci-2022-0229. eCollection 2022 Jan 1.
Depression is a common mood disorder characterised by high comorbidity with other mental and somatic diseases. New studies reveal a shared genetic base for mental core symptoms and somatic comorbidities. Functional analyses showed multiple brain-body pathways involved. This may help considering new therapeutic approaches for depression as a system's disorder.
抑郁症是一种常见的情绪障碍,其特征是与其他精神和躯体疾病高度共病。新的研究揭示了精神核心症状和躯体共病存在共同的遗传基础。功能分析表明涉及多个脑-身通路。这可能有助于将抑郁症视为一种系统性疾病来考虑新的治疗方法。