Clinical Neurosciences Division, National Center for PTSD, VA Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA.
Department of Psychiatry, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510, USA.
Psychol Med. 2023 Jul;53(10):4561-4568. doi: 10.1017/S0033291722001441. Epub 2022 Aug 12.
Cognitive processing therapy (CPT) and prolonged exposure (PE) delivered in an individual setting are efficacious and effective treatments for veterans with posttraumatic stress disorder (PTSD). Group CPT has been shown to be less efficacious than individual CPT, however, evidence regarding real-world effectiveness is limited.
We conducted a retrospective, observational, comparative effectiveness study including veterans that received at least eight sessions of group CPT, individual CPT, or individual PE, and were discharged from PTSD residential treatment at the Department of Veterans Affairs between 1 October 2015, and 30 September 2020. PTSD symptom severity was assessed with the PTSD Checklist for DSM-5 (PCL-5) and treatments delivered in a group (CPT) or individual (CPT or PE) setting were compared at discharge and 4-month post-discharge follow-up.
Of 6735 veterans, 3888 [653 women (17%), median (IQR) age 45 (35-55) years] received individual and 2847 [206 women (7.2%), median (IQR) age 42 (34-54)] received group therapy. At discharge, improvement in PTSD severity was statistically greater among those treated individually (mean difference on the PCL-5, 2.55 (95% CI 1.61-3.49); = <0.001]. However, the difference was smaller than the minimal clinically important difference of 7.9 points. The groups did not differ significantly at 4-month follow-up [mean difference on the PCL-5, 0.37 (95% CI -0.86 to 1.60); = 0.551].
Group CPT was associated with a slightly smaller reduction of PTSD symptom severity than individual CPT or PE in veterans at the end of residential treatment. There were no differences at 4-month follow-up.
认知加工疗法(CPT)和延长暴露疗法(PE)在个体治疗环境中对创伤后应激障碍(PTSD)退伍军人是有效的治疗方法。小组 CPT 的疗效不如个体 CPT,但关于实际有效性的证据有限。
我们进行了一项回顾性、观察性、比较有效性研究,纳入了 2015 年 10 月 1 日至 2020 年 9 月 30 日期间从退伍军人事务部 PTSD 住院治疗中出院的至少接受了 8 次小组 CPT、个体 CPT 或个体 PE 的退伍军人。使用 PTSD 检查表 DSM-5(PCL-5)评估 PTSD 症状严重程度,并在出院和出院后 4 个月随访时比较在小组(CPT)或个体(CPT 或 PE)环境中提供的治疗。
在 6735 名退伍军人中,3888 名(653 名女性[17%],中位数[IQR]年龄 45(35-55)岁)接受了个体治疗,2847 名(206 名女性[7.2%],中位数[IQR]年龄 42(34-54)]接受了小组治疗。在出院时,个体治疗组 PTSD 严重程度的改善在统计学上更为显著(PCL-5 上的平均差异,2.55(95%CI 1.61-3.49); = <0.001)。然而,这一差异小于 7.9 分的最小临床重要差异。两组在 4 个月随访时没有显著差异(PCL-5 上的平均差异,0.37(95%CI-0.86 至 1.60); = 0.551)。
在住院治疗结束时,小组 CPT 与 PTSD 症状严重程度的降低略小于个体 CPT 或 PE,在退伍军人中。在 4 个月的随访中没有差异。