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放疗可及性:从地方到全球,从平等到公平。

Access to Radiation Therapy: From Local to Global and Equality to Equity.

机构信息

Department of Radiation Oncology, Homi Bhabha National Institute, Tata Memorial Centre, Mumbai, India.

Department of Radiation Oncology and Danish Center for Particle Therapy, Aarhus University Hospital, Aarhus, Denmark.

出版信息

JCO Glob Oncol. 2022 Aug;8:e2100358. doi: 10.1200/GO.21.00358.

Abstract

The discipline of radiation oncology is the most resource-intensive component of comprehensive cancer care because of significant initial investments required for machines, the requirement of dedicated construction, a multifaceted workforce, and recurring maintenance costs. This review focuses on the challenges associated with accessible and affordable radiation therapy (RT) across the globe and the possible solutions to improve the current scenario. Most common cancers globally, including breast, prostate, head and neck, and cervical cancers, have a RT utilization rate of > 50%. The estimated annual incidence of cancer is 19,292,789 for 2020, with > 70% occurring in low-income countries and low-middle-income countries. There are approximately 14,000 teletherapy machines globally. However, the distribution of these machines is distinctly nonuniform, with low-income countries and low-middle-income countries having access to < 10% of the global teletherapy machines. The Directory of Radiotherapy Centres enlists 3,318 brachytherapy facilities. Most countries with a high incidence of cervical cancer have a deficit in brachytherapy facilities, although formal estimates for the same are not available. The deficit in simulators, radiation oncologists, and medical physicists is even more challenging to quantify; however, the inequitable distribution is indisputable. Measures to ensure equitable access to RT include identifying problems specific to region/country, adopting indigenous technology, encouraging public-private partnership, relaxing custom duties on RT equipment, global/cross-country collaboration, and quality human resources training. Innovative research focusing on the most prevalent cancers aiming to make RT utilization more cost-effective while maintaining efficacy will further bridge the gap.

摘要

放射肿瘤学是综合癌症治疗中资源最密集的专业,因为机器需要大量的初始投资,需要专用的建筑,需要多方面的劳动力,并且需要不断进行维护。本综述重点介绍了全球范围内可及且负担得起的放射治疗(RT)所面临的挑战,以及改善现状的可能解决方案。全球最常见的癌症,包括乳腺癌、前列腺癌、头颈部癌和宫颈癌,其 RT 使用率>50%。估计 2020 年全球癌症年发病率为 19,292,789 例,其中>70%发生在低收入国家和中低收入国家。全球约有 14000 台远距离治疗机。然而,这些机器的分布明显不均匀,低收入国家和中低收入国家仅能使用全球远距离治疗机的<10%。放射治疗中心名录列出了 3318 个近距离治疗设施。大多数宫颈癌发病率较高的国家都存在近距离治疗设施不足的情况,尽管没有关于这方面的正式估计数据。模拟器、肿瘤放射科医生和医学物理学家的短缺更难以量化,但分配不均是无可争议的。确保公平获得 RT 的措施包括确定特定地区/国家的问题,采用本土技术,鼓励公私伙伴关系,放宽 RT 设备的关税,开展全球/跨国合作,以及进行高质量的人力资源培训。专注于最常见癌症的创新性研究,旨在使 RT 利用更加具有成本效益,同时保持疗效,将进一步缩小差距。

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